| 产品: | SEPP1 抗体 |
| 货号: | DF8258 |
| 描述: | Rabbit polyclonal antibody to SEPP1 |
| 应用: | WB IHC |
| 反应: | Human, Rat, Monkey |
| 预测: | Pig |
| 分子量: | 43 kDa; 43kD(Calculated). |
| 蛋白号: | P49908 |
| RRID: | AB_2841548 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF8258, RRID:AB_2841548.
展开/折叠
Selenoprotein P; Selenoprotein P plasma 1; Selp; SeP; Sepp1; SEPP1_HUMAN;
抗原和靶标
A synthesized peptide derived from human SEPP1, corresponding to a region within the internal amino acids.
Made in the liver and heart and secreted into the plasma. It is also found in the kidney.
- P49908 SEPP1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MWRSLGLALALCLLPSGGTESQDQSSLCKQPPAWSIRDQDPMLNSNGSVTVVALLQASUYLCILQASKLEDLRVKLKKEGYSNISYIVVNHQGISSRLKYTHLKNKVSEHIPVYQQEENQTDVWTLLNGSKDDFLIYDRCGRLVYHLGLPFSFLTFPYVEEAIKIAYCEKKCGNCSLTTLKDEDFCKRVSLATVDKTVETPSPHYHHEHHHNHGHQHLGSSELSENQQPGAPNAPTHPAPPGLHHHHKHKGQHRQGHPENRDMPASEDLQDLQKKLCRKRCINQLLCKLPTDSELAPRSUCCHCRHLIFEKTGSAITUQCKENLPSLCSUQGLRAEENITESCQURLPPAAUQISQQLIPTEASASURUKNQAKKUEUPSN
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P49908 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| N83 | N-Glycosylation | Uniprot | |
| N119 | N-Glycosylation | Uniprot | |
| N128 | N-Glycosylation | Uniprot | |
| S190 | Phosphorylation | Uniprot | |
| S266 | Phosphorylation | Uniprot |
研究背景
Might be responsible for some of the extracellular antioxidant defense properties of selenium or might be involved in the transport of selenium. May supply selenium to tissues such as brain and testis.
Phosphorylation sites are present in the extracellular medium.
Secreted.
Note: Passes from plasma into the glomerular filtrate where it is removed by endocytosis mediated by LRP2 in the proximal tubule epithelium.
Made in the liver and heart and secreted into the plasma. It is also found in the kidney.
The C-terminus is not required for endocytic uptake in the proximal tubule epithelium.
Belongs to the selenoprotein P family.
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