| 产品: | CD2 Tail-binding 抗体 |
| 货号: | DF8644 |
| 描述: | Rabbit polyclonal antibody to CD2 Tail-binding |
| 应用: | WB IF/ICC |
| 反应: | Human, Mouse |
| 预测: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
| 分子量: | 37 kDa; 38kD(Calculated). |
| 蛋白号: | O95400 |
| RRID: | AB_2841848 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF8644, RRID:AB_2841848.
展开/折叠
CD2 (cytoplasmic tail) binding protein 2; CD2 antigen (cytoplasmic tail) binding protein 2; CD2 antigen cytoplasmic tail-binding protein 2; CD2 cytoplasmic domain-binding protein 2; CD2 tail-binding protein 2; CD2B2_HUMAN; Cd2bp2; FWP010; LIN1; Snu40; U5 snRNP 52K protein; U5-52K;
抗原和靶标
- O95400 CD2B2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MPKRKVTFQGVGDEEDEDEIIVPKKKLVDPVAGSGGPGSRFKGKHSLDSDEEEDDDDGGSSKYDILASEDVEGQEAATLPSEGGVRITPFNLQEEMEEGHFDADGNYFLNRDAQIRDSWLDNIDWVKIRERPPGQRQASDSEEEDSLGQTSMSAQALLEGLLELLLPRETVAGALRRLGARGGGKGRKGPGQPSSPQRLDRLSGLADQMVARGNLGVYQETRERLAMRLKGLGCQTLGPHNPTPPPSLDMFAEELAEEELETPTPTQRGEAESRGDGLVDVMWEYKWENTGDAELYGPFTSAQMQTWVSEGYFPDGVYCRKLDPPGGQFYNSKRIDFDLYT
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - O95400 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T7 | Phosphorylation | Uniprot | |
| K24 | Ubiquitination | Uniprot | |
| K26 | Sumoylation | Uniprot | |
| S34 | Phosphorylation | Uniprot | |
| S46 | Phosphorylation | Uniprot | |
| S49 | Phosphorylation | Uniprot | |
| S60 | Phosphorylation | Uniprot | |
| S61 | Phosphorylation | Uniprot | |
| Y107 | Phosphorylation | Uniprot | |
| S118 | Phosphorylation | Uniprot | |
| K127 | Ubiquitination | Uniprot | |
| S139 | Phosphorylation | Uniprot | |
| S141 | Phosphorylation | Uniprot | |
| T150 | Phosphorylation | Uniprot | |
| S151 | Phosphorylation | Uniprot | |
| R176 | Methylation | Uniprot | |
| R181 | Methylation | Uniprot | |
| S194 | Phosphorylation | Uniprot | |
| S195 | Phosphorylation | Uniprot | |
| T243 | Phosphorylation | Uniprot | |
| S247 | Phosphorylation | Uniprot | |
| T262 | Phosphorylation | Uniprot | |
| K321 | Sumoylation | Uniprot | |
| K321 | Ubiquitination | Uniprot | |
| Y330 | Phosphorylation | Uniprot | |
| S332 | Phosphorylation | Uniprot | |
| K333 | Acetylation | Uniprot | |
| K333 | Ubiquitination | Uniprot | |
| T341 | Phosphorylation | Uniprot |
研究背景
Involved in pre-mRNA splicing as component of the U5 snRNP complex that is involved in spliceosome assembly.
Cytoplasm. Nucleus.
Note: Predominantly nuclear.
Component of the U5 snRNP complex composed of the U5 snRNA and at least PRPF6, PRPF8, SNRNP200, EFTUD2, SNRNP40, DDX23, TXNL4A and CD2BP2. Interacts directly with TXNL4A and PRPF6. Interacts (via GYF domain) with CD2 (via Pro-rich sequence in the cytoplasmic domain). Interacts with PQBP1.
限制条款
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