| 产品: | CKLF 抗体 |
| 货号: | DF9374 |
| 描述: | Rabbit polyclonal antibody to CKLF |
| 应用: | WB IHC |
| 反应: | Human, Mouse, Rat |
| 预测: | Horse |
| 分子量: | 17 kDa; 17kD(Calculated). |
| 蛋白号: | Q9UBR5 |
| RRID: | AB_2842570 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF9374, RRID:AB_2842570.
展开/折叠
C32; Chemokine-like factor; chemokine-like factor 1; chemokine-like factor 2; chemokine-like factor 3; chemokine-like factor 4; CKLF1; CKLF2; CKLF3; CKLF4; CKLFSF2; HSPC224; transmembrane proteolipid; UCK-1; UCK1;
抗原和靶标
Isoform 1, isoform 2, isoform 3 and isoform 4 have highest expression levels in adult spleen, lung, testis, ovary, peripheral blood leukocyte, placenta, pancreas, and in fetal brain, skeletal muscle, thymus and heart. Lower expression levels in adult skeletal muscle, liver, thymus colon, prostate and fetal spleen and liver.
- Q9UBR5 CKLF_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MDNVQPKIKHRPFCFSVKGHVKMLRLALTVTSMTFFIIAQAPEPYIVITGFEVTVILFFILLYVLRLDRLMKWLFWPLLDIINSLVTTVFMLIVSVLALIPETTTLTVGGGVFALVTAVCCLADGALIYRKLLFNPSGPYQKKPVHEKKEVL
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q9UBR5 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K7 | Ubiquitination | Uniprot | |
| K9 | Ubiquitination | Uniprot | |
| K18 | Methylation | Uniprot | |
| K22 | Methylation | Uniprot | |
| K131 | Ubiquitination | Uniprot | |
| S137 | Phosphorylation | Uniprot | |
| Y140 | Phosphorylation | Uniprot |
研究背景
May play an important role in inflammation and regeneration of skeletal muscle. Partly inhibited by interleukin 10.
has chemotactic response in monocytes, neutrophils and lymphocytes. Binds CCR4.
Secreted.
Membrane>Multi-pass membrane protein.
Membrane>Multi-pass membrane protein.
Isoform 1, isoform 2, isoform 3 and isoform 4 have highest expression levels in adult spleen, lung, testis, ovary, peripheral blood leukocyte, placenta, pancreas, and in fetal brain, skeletal muscle, thymus and heart. Lower expression levels in adult skeletal muscle, liver, thymus colon, prostate and fetal spleen and liver.
Belongs to the chemokine-like factor family.
限制条款
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