| 产品: | CSDE1 抗体 |
| 货号: | DF12920 |
| 描述: | Rabbit polyclonal antibody to CSDE1 |
| 应用: | WB |
| 反应: | Human, Mouse |
| 预测: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken |
| 分子量: | 89 kDa; 89kD(Calculated). |
| 蛋白号: | O75534 |
| RRID: | AB_2845881 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF12920, RRID:AB_2845881.
展开/折叠
Cold shock domain containing E1 RNA binding; Cold shock domain containing protein E1; Cold shock domain-containing protein E1; Csde1; CSDE1_HUMAN; D1S155E; DKFZp779B0247; DKFZp779J1455; FLJ26882; N-ras upstream gene protein; NRAS related; Nras upstream gene protein; NRU; Protein UNR; RP5 1000E10.3; UNR; UNR protein; Upstream of NRAS;
抗原和靶标
- O75534 CSDE1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSFDPNLLHNNGHNGYPNGTSAALRETGVIEKLLTSYGFIQCSERQARLFFHCSQYNGNLQDLKVGDDVEFEVSSDRRTGKPIAVKLVKIKQEILPEERMNGQVVCAVPHNLESKSPAAPGQSPTGSVCYERNGEVFYLTYTPEDVEGNVQLETGDKINFVIDNNKHTGAVSARNIMLLKKKQARCQGVVCAMKEAFGFIERGDVVKEIFFHYSEFKGDLETLQPGDDVEFTIKDRNGKEVATDVRLLPQGTVIFEDISIEHFEGTVTKVIPKVPSKNQNDPLPGRIKVDFVIPKELPFGDKDTKSKVTLLEGDHVRFNISTDRRDKLERATNIEVLSNTFQFTNEAREMGVIAAMRDGFGFIKCVDRDVRMFFHFSEILDGNQLHIADEVEFTVVPDMLSAQRNHAIRIKKLPKGTVSFHSHSDHRFLGTVEKEATFSNPKTTSPNKGKEKEAEDGIIAYDDCGVKLTIAFQAKDVEGSTSPQIGDKVEFSISDKQRPGQQVATCVRLLGRNSNSKRLLGYVATLKDNFGFIETANHDKEIFFHYSEFSGDVDSLELGDMVEYSLSKGKGNKVSAEKVNKTHSVNGITEEADPTIYSGKVIRPLRSVDPTQTEYQGMIEIVEEGDMKGEVYPFGIVGMANKGDCLQKGESVKFQLCVLGQNAQTMAYNITPLRRATVECVKDQFGFINYEVGDSKKLFFHVKEVQDGIELQAGDEVEFSVILNQRTGKCSACNVWRVCEGPKAVAAPRPDRLVNRLKNITLDDASAPRLMVLRQPRGPDNSMGFGAERKIRQAGVID
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - O75534 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S2 | Phosphorylation | Uniprot | |
| K32 | Ubiquitination | Uniprot | |
| K81 | Acetylation | Uniprot | |
| K81 | Ubiquitination | Uniprot | |
| K86 | Ubiquitination | Uniprot | |
| K91 | Sumoylation | Uniprot | |
| K91 | Ubiquitination | Uniprot | |
| S116 | Phosphorylation | Uniprot | |
| S123 | Phosphorylation | Uniprot | |
| S127 | Phosphorylation | Uniprot | |
| Y138 | Phosphorylation | Uniprot | |
| K166 | Ubiquitination | Uniprot | |
| K180 | Ubiquitination | Uniprot | |
| K194 | Ubiquitination | Uniprot | |
| K207 | Ubiquitination | Uniprot | |
| K234 | Ubiquitination | Uniprot | |
| K239 | Acetylation | Uniprot | |
| K239 | Ubiquitination | Uniprot | |
| K273 | Ubiquitination | Uniprot | |
| S276 | Phosphorylation | Uniprot | |
| K277 | Ubiquitination | Uniprot | |
| K288 | Ubiquitination | Uniprot | |
| K295 | Ubiquitination | Uniprot | |
| K302 | Ubiquitination | Uniprot | |
| K307 | Ubiquitination | Uniprot | |
| R324 | Methylation | Uniprot | |
| K364 | Acetylation | Uniprot | |
| K364 | Ubiquitination | Uniprot | |
| K415 | Ubiquitination | Uniprot | |
| S419 | Phosphorylation | Uniprot | |
| S422 | Phosphorylation | Uniprot | |
| S424 | Phosphorylation | Uniprot | |
| T431 | Phosphorylation | Uniprot | |
| K434 | Acetylation | Uniprot | |
| K434 | Ubiquitination | Uniprot | |
| K442 | Ubiquitination | Uniprot | |
| T443 | Phosphorylation | Uniprot | |
| T444 | Phosphorylation | Uniprot | |
| S445 | Phosphorylation | Uniprot | |
| K452 | Ubiquitination | Uniprot | |
| T481 | Phosphorylation | Uniprot | |
| S482 | Phosphorylation | Uniprot | |
| K488 | Ubiquitination | Uniprot | |
| K496 | Ubiquitination | Uniprot | |
| S514 | Phosphorylation | Uniprot | |
| T525 | Phosphorylation | Uniprot | |
| K527 | Ubiquitination | Uniprot | |
| K578 | Ubiquitination | Uniprot | |
| K581 | Ubiquitination | Uniprot | |
| S584 | Phosphorylation | Uniprot | |
| Y597 | Phosphorylation | Uniprot | |
| K600 | Ubiquitination | Uniprot | |
| S607 | Phosphorylation | Uniprot | |
| K628 | Sumoylation | Uniprot | |
| K642 | Ubiquitination | Uniprot | |
| K648 | Acetylation | Uniprot | |
| K648 | Ubiquitination | Uniprot | |
| T677 | Phosphorylation | Uniprot | |
| K682 | Acetylation | Uniprot | |
| K682 | Ubiquitination | Uniprot | |
| Y690 | Phosphorylation | Uniprot | |
| K696 | Acetylation | Uniprot | |
| K696 | Ubiquitination | Uniprot | |
| K697 | Acetylation | Uniprot | |
| K697 | Ubiquitination | Uniprot | |
| K729 | Ubiquitination | Uniprot | |
| K743 | Ubiquitination | Uniprot | |
| R749 | Methylation | Uniprot | |
| R752 | Methylation | Uniprot | |
| K758 | Ubiquitination | Uniprot | |
| T761 | Phosphorylation | Uniprot | |
| S782 | Phosphorylation | Uniprot |
研究背景
RNA-binding protein. Required for internal initiation of translation of human rhinovirus RNA. May be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain.
Cytoplasm.
Component of a multi subunit autoregulatory ribonucleoprotein complex (ARC), at least composed of IGF2BP1, PABPC1 and CSDE1. Interacts with STRAP. Part of a complex associated with the FOS mCRD domain and consisting of PABPC1, PAIP1, HNRPD and SYNCRIP. The interaction with PABPC1 is direct and RNA-independent.
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