CSDE1 Antibody - #DF12920

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产品: CSDE1 抗体
货号: DF12920
描述: Rabbit polyclonal antibody to CSDE1
应用: WB
反应: Human, Mouse
预测: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken
分子量: 89 kDa; 89kD(Calculated).
蛋白号: O75534
RRID: AB_2845881

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   规格 价格 库存
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse
预测:
Pig(100%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(92%), Dog(100%), Chicken(100%)
克隆:
Polyclonal
特异性:
CSDE1 Antibody detects endogenous levels of total CSDE1.
RRID:
AB_2845881
引用格式: Affinity Biosciences Cat# DF12920, RRID:AB_2845881.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

Cold shock domain containing E1 RNA binding; Cold shock domain containing protein E1; Cold shock domain-containing protein E1; Csde1; CSDE1_HUMAN; D1S155E; DKFZp779B0247; DKFZp779J1455; FLJ26882; N-ras upstream gene protein; NRAS related; Nras upstream gene protein; NRU; Protein UNR; RP5 1000E10.3; UNR; UNR protein; Upstream of NRAS;

抗原和靶标

免疫原:
Uniprot:

O75534(CSDE1_HUMAN) >>Visit HPA database.

基因/基因ID:
CSDE1(7812)
序列:
MSFDPNLLHNNGHNGYPNGTSAALRETGVIEKLLTSYGFIQCSERQARLFFHCSQYNGNLQDLKVGDDVEFEVSSDRRTGKPIAVKLVKIKQEILPEERMNGQVVCAVPHNLESKSPAAPGQSPTGSVCYERNGEVFYLTYTPEDVEGNVQLETGDKINFVIDNNKHTGAVSARNIMLLKKKQARCQGVVCAMKEAFGFIERGDVVKEIFFHYSEFKGDLETLQPGDDVEFTIKDRNGKEVATDVRLLPQGTVIFEDISIEHFEGTVTKVIPKVPSKNQNDPLPGRIKVDFVIPKELPFGDKDTKSKVTLLEGDHVRFNISTDRRDKLERATNIEVLSNTFQFTNEAREMGVIAAMRDGFGFIKCVDRDVRMFFHFSEILDGNQLHIADEVEFTVVPDMLSAQRNHAIRIKKLPKGTVSFHSHSDHRFLGTVEKEATFSNPKTTSPNKGKEKEAEDGIIAYDDCGVKLTIAFQAKDVEGSTSPQIGDKVEFSISDKQRPGQQVATCVRLLGRNSNSKRLLGYVATLKDNFGFIETANHDKEIFFHYSEFSGDVDSLELGDMVEYSLSKGKGNKVSAEKVNKTHSVNGITEEADPTIYSGKVIRPLRSVDPTQTEYQGMIEIVEEGDMKGEVYPFGIVGMANKGDCLQKGESVKFQLCVLGQNAQTMAYNITPLRRATVECVKDQFGFINYEVGDSKKLFFHVKEVQDGIELQAGDEVEFSVILNQRTGKCSACNVWRVCEGPKAVAAPRPDRLVNRLKNITLDDASAPRLMVLRQPRGPDNSMGFGAERKIRQAGVID

种属预测

种属预测:

score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Chicken
100
Rabbit
92
Xenopus
75
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - O75534 作为底物

Site PTM Type Enzyme
S2 Phosphorylation
K32 Ubiquitination
K81 Acetylation
K81 Ubiquitination
K86 Ubiquitination
K91 Sumoylation
K91 Ubiquitination
S116 Phosphorylation
S123 Phosphorylation
S127 Phosphorylation
Y138 Phosphorylation
K166 Ubiquitination
K180 Ubiquitination
K194 Ubiquitination
K207 Ubiquitination
K234 Ubiquitination
K239 Acetylation
K239 Ubiquitination
K273 Ubiquitination
S276 Phosphorylation
K277 Ubiquitination
K288 Ubiquitination
K295 Ubiquitination
K302 Ubiquitination
K307 Ubiquitination
R324 Methylation
K364 Acetylation
K364 Ubiquitination
K415 Ubiquitination
S419 Phosphorylation
S422 Phosphorylation
S424 Phosphorylation
T431 Phosphorylation
K434 Acetylation
K434 Ubiquitination
K442 Ubiquitination
T443 Phosphorylation
T444 Phosphorylation
S445 Phosphorylation
K452 Ubiquitination
T481 Phosphorylation
S482 Phosphorylation
K488 Ubiquitination
K496 Ubiquitination
S514 Phosphorylation
T525 Phosphorylation
K527 Ubiquitination
K578 Ubiquitination
K581 Ubiquitination
S584 Phosphorylation
Y597 Phosphorylation
K600 Ubiquitination
S607 Phosphorylation
K628 Sumoylation
K642 Ubiquitination
K648 Acetylation
K648 Ubiquitination
T677 Phosphorylation
K682 Acetylation
K682 Ubiquitination
Y690 Phosphorylation
K696 Acetylation
K696 Ubiquitination
K697 Acetylation
K697 Ubiquitination
K729 Ubiquitination
K743 Ubiquitination
R749 Methylation
R752 Methylation
K758 Ubiquitination
T761 Phosphorylation
S782 Phosphorylation

研究背景

功能:

RNA-binding protein. Required for internal initiation of translation of human rhinovirus RNA. May be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain.

细胞定位:

Cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
亚基结构:

Component of a multi subunit autoregulatory ribonucleoprotein complex (ARC), at least composed of IGF2BP1, PABPC1 and CSDE1. Interacts with STRAP. Part of a complex associated with the FOS mCRD domain and consisting of PABPC1, PAIP1, HNRPD and SYNCRIP. The interaction with PABPC1 is direct and RNA-independent.

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