产品: DAP3 抗体
货号: DF13390
描述: Rabbit polyclonal antibody to DAP3
应用: WB
反应: Human, Mouse, Rat
预测: Pig, Bovine, Horse, Sheep, Rabbit, Dog
分子量: 45kDa; 46kD(Calculated).
蛋白号: P51398
RRID: AB_2846409

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   规格 价格 库存
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse,Rat
预测:
Pig(88%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(88%), Dog(100%)
克隆:
Polyclonal
特异性:
DAP3 Antibody detects endogenous levels of total DAP3.
RRID:
AB_2846409
引用格式: Affinity Biosciences Cat# DF13390, RRID:AB_2846409.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

28S ribosomal protein S29; 28S ribosomal protein S29 mitochondrial; bMRP10; DAP 3; DAP-3; Dap3; Death associated protein 3; Death-associated protein 3; DKFZp686G12159; FLJ12817; Ionizing radiation resistance conferring protein; MGC126058; MGC126059; Mitochondrial 28S ribosomal protein S29; mitochondrial; MITOCHONDRIAL RIBOSOMAL PROTEIN S29; MRP S29; MRP-S29; MRPS29; OTTHUMP00000033480; OTTHUMP00000033481; PSD-95/SAP90-binding protein 3; RT29_HUMAN; S29mt; SAP90/PSD-95-associated protein 3; SAPAP3;

抗原和靶标

免疫原:
Uniprot:
基因/基因ID:
表达:
P51398 RT29_HUMAN:

Ubiquitous.

序列:
MMLKGITRLISRIHKLDPGRFLHMGTQARQSIAAHLDNQVPVESPRAISRTNENDPAKHGDQHEGQHYNISPQDLETVFPHGLPPRFVMQVKTFSEACLMVRKPALELLHYLKNTSFAYPAIRYLLYGEKGTGKTLSLCHVIHFCAKQDWLILHIPDAHLWVKNCRDLLQSSYNKQRFDQPLEASTWLKNFKTTNERFLNQIKVQEKYVWNKRESTEKGSPLGEVVEQGITRVRNATDAVGIVLKELKRQSSLGMFHLLVAVDGINALWGRTTLKREDKSPIAPEELALVHNLRKMMKNDWHGGAIVSALSQTGSLFKPRKAYLPQELLGKEGFDALDPFIPILVSNYNPKEFESCIQYYLENNWLQHEKAPTEEGKKELLFLSNANPSLLERHCAYL

种属预测

种属预测:

score>80的预测可信度较高,可尝试用于WB检测。*预测模型主要基于免疫原序列比对,结果仅作参考,不作为质保凭据。

Species
Results
Score
Horse
100
Bovine
100
Sheep
100
Dog
100
Pig
88
Rabbit
88
Chicken
75
Xenopus
0
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - P51398 作为底物

Site PTM Type Enzyme
S31 Phosphorylation Q05655 (PRKCD) , P17612 (PRKACA)
S44 Phosphorylation
T93 Phosphorylation
K103 Ubiquitination
Y124 Phosphorylation
K130 Ubiquitination
K175 Acetylation
K175 Ubiquitination
S185 Phosphorylation Q05655 (PRKCD) , P17612 (PRKACA)
T186 Phosphorylation Q05655 (PRKCD) , P17612 (PRKACA)
K189 Ubiquitination
K192 Ubiquitination
K203 Ubiquitination
K207 Acetylation
K207 Ubiquitination
S215 Phosphorylation
T216 Phosphorylation
K218 Ubiquitination
S220 Phosphorylation P17612 (PRKACA)
T231 Phosphorylation
T237 Phosphorylation Q05655 (PRKCD)
K245 Ubiquitination
S251 Phosphorylation
S252 Phosphorylation
T272 Phosphorylation
T273 Phosphorylation
K279 Ubiquitination
S280 Phosphorylation Q05655 (PRKCD)
S311 Phosphorylation
K318 Ubiquitination
K321 Ubiquitination
K370 Ubiquitination
K378 Ubiquitination
S389 Phosphorylation

研究背景

功能:

Involved in mediating interferon-gamma-induced cell death.

细胞定位:

Mitochondrion.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Ubiquitous.

亚基结构:

Component of the mitochondrial small ribosomal subunit (mt-SSU). Mature mammalian 55S mitochondrial ribosomes consist of a small (28S) and a large (39S) subunit. The 28S small subunit contains a 12S ribosomal RNA (12S mt-rRNA) and 30 different proteins. The 39S large subunit contains a 16S rRNA (16S mt-rRNA), a copy of mitochondrial valine transfer RNA (mt-tRNA(Val)), which plays an integral structural role, and 52 different proteins. Interacts with DELE1. Interacts with NOA1.

蛋白家族:

Belongs to the mitochondrion-specific ribosomal protein mS29 family.

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