产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
展开/折叠
8030446C20Rik; AI649009; FLJ38499; GLD 2; Gld2; GLD2_HUMAN; hGLD 2; hGLD-2; MGC93684; PAD 4; PAP associated domain containing 4; PAP-associated domain-containing protein 4; papd4; Poly(A) RNA polymerase GLD2; Terminal uridylyltransferase 2; TUTase 2;
抗原和靶标
A synthesized peptide derived from Human PAPD4.
Expressed in brain. Within brain, it is expressed in cerebellum, hippocampus and medulla.
- Q6PIY7 GLD2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MFPNSILGRPPFTPNHQQHNNFFTLSPTVYSHQQLIDAQFNFQNADLSRAVSLQQLTYGNVSPIQTSASPLFRGRKRLSDEKNLPLDGKRQRFHSPHQEPTVVNQIVPLSGERRYSMPPLFHTHYVPDIVRCVPPFREIAFLEPREITLPEAKDKLSQQILELFETCQQQISDLKKKELCRTQLQREIQLLFPQSRLFLVGSSLNGFGTRSSDGDLCLVVKEEPCFFQVNQKTEARHILTLVHKHFCTRLSGYIERPQLIRAKVPIVKFRDKVSCVEFDLNVNNIVGIRNTFLLRTYAYLENRVRPLVLVIKKWASHHQINDASRGTLSSYSLVLMVLHYLQTLPEPILPSLQKIYPESFSPAIQLHLVHQAPCNVPPYLSKNESNLGDLLLGFLKYYATEFDWNSQMISVREAKAIPRPDGIEWRNKYICVEEPFDGTNTARAVHEKQKFDMIKDQFLKSWHRLKNKRDLNSILPVRAAVLKR
研究背景
Cytoplasmic poly(A) RNA polymerase that adds successive AMP monomers to the 3'-end of specific RNAs, forming a poly(A) tail. In contrast to the canonical nuclear poly(A) RNA polymerase, it only adds poly(A) to selected cytoplasmic mRNAs. Does not play a role in replication-dependent histone mRNA degradation. Adds a single nucleotide to the 3' end of specific miRNAs, monoadenylation stabilizes and prolongs the activity of some but not all miRNAs.
Cytoplasm. Nucleus.
Expressed in brain. Within brain, it is expressed in cerebellum, hippocampus and medulla.
Interacts with CPEB1, CPEB2, CPSF1 and PABPC1.
Belongs to the DNA polymerase type-B-like family. GLD2 subfamily.
限制条款
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