产品: | ZDHHC13 抗体 |
货号: | DF2600 |
描述: | Rabbit polyclonal antibody to ZDHHC13 |
应用: | WB IHC |
反应: | Human, Monkey |
预测: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
分子量: | 58 kDa; 71kD(Calculated). |
蛋白号: | Q8IUH4 |
RRID: | AB_2839806 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF2600, RRID:AB_2839806.
展开/折叠
DHHC 13; DHHC-13; FLJ10852; FLJ10941; HIP14 like; HIP14 related protein; HIP14-related protein; HIP14L; HIP3RP; Huntingtin interacting protein 14 related protein; Huntingtin interacting protein HIP3RP; Huntingtin-interacting protein 14-related protein; Huntingtin-interacting protein HIP3RP; Hypothetical protein similar to ankyrin repeat containing priotein AKR1; MGC64994; Palmitoyltransferase ZDHHC13; Probable palmitoyltransferase ZDHHC13; Putative MAPK activating protein PM03; Putative MAPK-activating protein PM03; Putative NF kappa B activating protein 209; Putative NF-kappa-B-activating protein 209; ZDH13_HUMAN; ZDHHC 13; ZDHHC13; Zinc finger DHHC domain containing 13; Zinc finger DHHC domain-containing protein 13;
抗原和靶标
- Q8IUH4 ZDH13_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MEGPGLGSQCRNHSHGPHPPGFGRYGICAHENKELANAREALPLIEDSSNCDIVKATQYGIFERCKELVEAGYDVRQPDKENVSLLHWAAINNRLDLVKFYISKGAVVDQLGGDLNSTPLHWAIRQGHLPMVILLLQHGADPTLIDGEGFSSIHLAVLFQHMPIIAYLISKGQSVNMTDVNGQTPLMLSAHKVIGPEPTGFLLKFNPSLNVVDKIHQNTPLHWAVAAGNVNAVDKLLEAGSSLDIQNVKGETPLDMALQNKNQLIIHMLKTEAKMRANQKFRLWRWLQKCELFLLLMLSVITMWAIGYILDFNSDSWLLKGCLLVTLFFLTSLFPRFLVGYKNLVYLPTAFLLSSVFWIFMTWFILFFPDLAGAPFYFSFIFSIVAFLYFFYKTWATDPGFTKASEEEKKVNIITLAETGSLDFRTFCTSCLIRKPLRSLHCHVCNCCVARYDQHCLWTGRCIGFGNHHYYIFFLFFLSMVCGWIIYGSFIYLSSHCATTFKEDGLWTYLNQIVACSPWVLYILMLATFHFSWSTFLLLNQLFQIAFLGLTSHERISLQKQSKHMKQTLSLRKTPYNLGFMQNLADFFQCGCFGLVKPCVVDWTSQYTMVFHPAREKVLRSV
种属预测
score>80的预测可信度较高,可尝试用于WB检测。*预测模型主要基于免疫原序列比对,结果仅作参考,不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q8IUH4 作为底物
Site | PTM Type | Enzyme | Source |
---|---|---|---|
M1 | Acetylation | Uniprot | |
S8 | Phosphorylation | Uniprot | |
Y25 | Phosphorylation | Uniprot | |
K33 | Ubiquitination | Uniprot | |
K55 | Ubiquitination | Uniprot | |
Y59 | Phosphorylation | Uniprot | |
K66 | Ubiquitination | Uniprot | |
Y73 | Phosphorylation | Uniprot | |
R76 | Methylation | Uniprot | |
K80 | Ubiquitination | Uniprot | |
K192 | Ubiquitination | Uniprot | |
K214 | Ubiquitination | Uniprot | |
K235 | Ubiquitination | Uniprot | |
K249 | Ubiquitination | Uniprot | |
K261 | Ubiquitination | Uniprot | |
K566 | Ubiquitination | Uniprot |
研究背景
Palmitoyltransferase for HTT and GAD2. May play a role in Mg(2+) transport.
Golgi apparatus membrane>Multi-pass membrane protein. Cytoplasmic vesicle membrane>Multi-pass membrane protein.
Note: Low extracellular Mg(2+) induces increase in Golgi and in post-Golgi vesicles.
Interacts (via ANK repeats) with CLIP3. Interacts (via ANK repeats) with DNAJC5 (via C-terminus) (By similarity). Interacts (via ANK repeats) with HTT. Interacts (via ANK repeats) with MAP6. Interacts (via ANK repeats) with SNAP23. Interacts (via ANK repeats) with SNAP25. May interact (via ANK repeats) with SPRED2 (By similarity).
The DHHC domain is required for palmitoyltransferase activity.
Belongs to the DHHC palmitoyltransferase family. AKR/ZDHHC17 subfamily.
文献引用
Application: WB Species: Human Sample: A375 cells
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