ATP6V1B2 Antibody - #DF10004

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产品: ATP6V1B2 抗体
货号: DF10004
描述: Rabbit polyclonal antibody to ATP6V1B2
应用: WB
反应: Human, Mouse, Rat
预测: Pig, Zebrafish, Bovine, Horse, Rabbit, Dog, Chicken, Xenopus
分子量: 57 kDa; 57kD(Calculated).
蛋白号: P21281
RRID: AB_2840584

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   规格 价格 库存
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

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产品描述

来源:
Rabbit
应用:
WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse,Rat
预测:
Pig(100%), Zebrafish(91%), Bovine(100%), Horse(100%), Rabbit(100%), Dog(100%), Chicken(82%), Xenopus(83%)
克隆:
Polyclonal
特异性:
ATP6V1B2 Antibody detects endogenous levels of total ATP6V1B2.
RRID:
AB_2840584
引用格式: Affinity Biosciences Cat# DF10004, RRID:AB_2840584.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

ATP6B1B2; ATP6B2; ATP6V1 B2; ATP6V1B 2; ATP6V1B2; ATPase H+ transporting lysosomal 56/58kDa V1 subunit B isoform 2; ATPase H+ transporting lysosomal 56/58kDa V1 subunit B2; ATPase H+ transporting, lysosomal (vacuolar proton pump) beta polypeptide 56/58kD isoform 2; ATPase, H+ transporting, lysosomal V1 subunit B2; brain isoform; Endomembrane proton pump 58 kDa subunit; H+ transporting two sector ATPase; HO 57; HO57; V ATPase B2 subunit; V ATPase subunit B 2; V type proton ATPase subunit B, brain isoform; V-ATPase subunit B 2; V-type proton ATPase subunit B; Vacuolar ATP synthase subunit B brain isoform; Vacuolar H+ ATPase 56,000 subunit; Vacuolar H+ ATPase 56000 subunit; Vacuolar H+ATPase B2; Vacuolar proton pump subunit B 2; VAT B2; VATB 2; VATB; VATB2; VATB2_HUMAN; Vma 2; Vma2; VPP 3; VPP3;

抗原和靶标

免疫原:
Uniprot:

P21281(VATB2_HUMAN) >>Visit HPA database.

基因/基因ID:
ATP6V1B2(526)
序列:
MALRAMRGIVNGAAPELPVPTGGPAVGAREQALAVSRNYLSQPRLTYKTVSGVNGPLVILDHVKFPRYAEIVHLTLPDGTKRSGQVLEVSGSKAVVQVFEGTSGIDAKKTSCEFTGDILRTPVSEDMLGRVFNGSGKPIDRGPVVLAEDFLDIMGQPINPQCRIYPEEMIQTGISAIDGMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVKKSKDVVDYSEENFAIVFAAMGVNMETARFFKSDFEENGSMDNVCLFLNLANDPTIERIITPRLALTTAEFLAYQCEKHVLVILTDMSSYAEALREVSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIYVDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTRKDHADVSNQLYACYAIGKDVQAMKAVVGEEALTSDDLLYLEFLQKFERNFIAQGPYENRTVFETLDIGWQLLRIFPKEMLKRIPQSTLSEFYPRDSAKH

种属预测

种属预测:

score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Dog
100
Rabbit
100
Zebrafish
91
Xenopus
83
Chicken
82
Sheep
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - P21281 作为底物

Site PTM Type Enzyme
R4 Methylation
R7 Methylation
Y39 Phosphorylation
S41 Phosphorylation
R44 Methylation
K48 Ubiquitination
T49 Phosphorylation
S51 Phosphorylation
K64 Ubiquitination
R67 Methylation
S83 Phosphorylation
K108 Acetylation
K108 Ubiquitination
K109 Ubiquitination
C112 S-Nitrosylation
S124 Phosphorylation
K137 Ubiquitination
S182 Phosphorylation
R185 Methylation
K188 Ubiquitination
Y222 Phosphorylation
Y328 Phosphorylation
Y389 Phosphorylation
S397 Phosphorylation
S399 Phosphorylation
K403 Ubiquitination
K457 Ubiquitination
R460 Methylation
R506 Methylation

研究背景

功能:

Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.

细胞定位:

Endomembrane system>Peripheral membrane protein. Melanosome.
Note: Endomembrane. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
亚基结构:

V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (main components: subunits A, B, C, D, E, and F) attached to an integral membrane V0 proton pore complex (main component: the proteolipid protein).

蛋白家族:

Belongs to the ATPase alpha/beta chains family.

研究领域

· Cellular Processes > Transport and catabolism > Phagosome.   (View pathway)

· Environmental Information Processing > Signal transduction > mTOR signaling pathway.   (View pathway)

· Human Diseases > Infectious diseases: Bacterial > Vibrio cholerae infection.

· Human Diseases > Infectious diseases: Bacterial > Epithelial cell signaling in Helicobacter pylori infection.

· Human Diseases > Immune diseases > Rheumatoid arthritis.

· Metabolism > Energy metabolism > Oxidative phosphorylation.

· Metabolism > Global and overview maps > Metabolic pathways.

· Organismal Systems > Nervous system > Synaptic vesicle cycle.

· Organismal Systems > Excretory system > Collecting duct acid secretion.

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