FDFT1 Antibody - #DF8121

(2)  
产品: FDFT1 抗体
货号: DF8121
描述: Rabbit polyclonal antibody to FDFT1
应用: WB IHC
反应: Human
预测: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken
分子量: 48 kDa; 48kD(Calculated).
蛋白号: P37268
RRID: AB_2841461

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   规格 价格 库存
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

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产品描述

来源:
Rabbit
应用:
WB 1:1000-3000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human
预测:
Pig(92%), Bovine(83%), Horse(92%), Sheep(92%), Rabbit(100%), Dog(92%), Chicken(92%)
克隆:
Polyclonal
特异性:
FDFT1 Antibody detects endogenous levels of total FDFT1.
RRID:
AB_2841461
引用格式: Affinity Biosciences Cat# DF8121, RRID:AB_2841461.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

DGPT; ERG9; Farnesyl diphosphate farnesyltransferase; Farnesyl-diphosphate farnesyltransferase; FDFT_HUMAN; FDFT1; FPP:FPP farnesyltransferase; SQS; Squalene synthase; Squalene synthetase; SS;

抗原和靶标

免疫原:
Uniprot:

P37268(FDFT_HUMAN) >>Visit HPA database.

基因/基因ID:
FDFT1(2222)
表达:
P37268 FDFT_HUMAN:

Widely expressed.

序列:
MEFVKCLGHPEEFYNLVRFRIGGKRKVMPKMDQDSLSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFAKPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVKIRKGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSDPSSSKTRQIISTIRTQNLPNCQLISRSHYSPIYLSFVMLLAALSWQYLTTLSQVTEDYVQTGEH

种属预测

种属预测:

score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。

Species
Results
Score
Rabbit
100
Pig
92
Horse
92
Sheep
92
Dog
92
Chicken
92
Bovine
83
Xenopus
0
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - P37268 作为底物

Site PTM Type Enzyme
K5 Ubiquitination
C6 S-Nitrosylation
Y14 Phosphorylation
K30 Ubiquitination
K41 Ubiquitination
K45 Ubiquitination
K92 Ubiquitination
K93 Ubiquitination
K115 Ubiquitination
K117 Ubiquitination
T127 Phosphorylation
S129 Phosphorylation
K138 Ubiquitination
K160 Ubiquitination
S164 Phosphorylation
K213 Ubiquitination
K318 Ubiquitination
Y346 Phosphorylation
S352 Phosphorylation
K358 Ubiquitination

研究背景

细胞定位:

Endoplasmic reticulum membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Widely expressed.

亚基结构:

Monomer.

蛋白家族:

Belongs to the phytoene/squalene synthase family.

研究领域

· Metabolism > Lipid metabolism > Steroid biosynthesis.

· Metabolism > Global and overview maps > Metabolic pathways.

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