PGE synthase Antibody - #DF8592

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产品: PGE synthase 抗体
货号: DF8592
描述: Rabbit polyclonal antibody to PGE synthase
应用: WB IHC
反应: Human, Mouse, Rat
预测: Bovine, Horse, Sheep, Rabbit, Dog, Chicken
分子量: 17 kDa; 17kD(Calculated).
蛋白号: O14684
RRID: AB_2841796

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   规格 价格 库存
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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MS Report
HPLC Report
MSDS
说明书
COA
实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:1000-3000, IHC 1:50-200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse,Rat
预测:
Bovine(92%), Horse(91%), Sheep(92%), Rabbit(100%), Dog(83%), Chicken(91%)
克隆:
Polyclonal
特异性:
PGE synthase Antibody detects endogenous levels of total PGE synthase.
RRID:
AB_2841796
引用格式: Affinity Biosciences Cat# DF8592, RRID:AB_2841796.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

Glutathione S transferase 1 like 1; MGC10317; MGST IV; MGST1 L1; MGST1 like 1; MGST1-L1; MGST1L1; MGSTIV; Microsomal glutathione S transferase 1 like 1; Microsomal glutathione S-transferase 1-like 1; Microsomal prostaglandin E synthase 1; Microsomal prostaglandin E synthase 1; mPGES 1; MPGES; mPGES-1; p53 induced apoptosis protein 12; p53 induced gene 12; p53 induced gene 12 protein; p53-induced gene 12 protein; PGES; PIG 12; PIG12; PP 102; PP 1294; PP102; PP1294; Prostaglandin E synthase; PTGES; PTGES_HUMAN; TP53I12; Tumor protein p53 inducible protein 12;

抗原和靶标

免疫原:
Uniprot:

O14684(PTGES_HUMAN) >>Visit HPA database.

基因/基因ID:
PTGES(9536)
序列:
MPAHSLVMSSPALPAFLLCSTLLVIKMYVVAIITGQVRLRKKAFANPEDALRHGGPQYCRSDPDVERCLRAHRNDMETIYPFLFLGFVYSFLGPNPFVAWMHFLVFLVGRVAHTVAYLGKLRAPIRSVTYTLAQLPCASMALQILWEAARHL

种属预测

种属预测:

score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。

Species
Results
Score
Rabbit
100
Bovine
92
Sheep
92
Horse
91
Chicken
91
Dog
83
Zebrafish
67
Pig
0
Xenopus
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

研究背景

功能:

Catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2).

细胞定位:

Membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
亚基结构:

Homotrimer.

蛋白家族:

Belongs to the MAPEG family.

研究领域

· Metabolism > Lipid metabolism > Arachidonic acid metabolism.

· Metabolism > Global and overview maps > Metabolic pathways.

文献引用

1). Kiwi Root Extract Inhibits the Development of Endometriosis in Mice by Downregulating Inflammatory Factors. Evidence-based Complementary and Alternative Medicine (PubMed: 33574880)

Application: WB    Species: Mice    Sample: endometriotic tissue

Figure 6 The expression of COX-1, COX-2, and EP2 mRNA and the expression of COX-1, COX-2, mPGEs, EP2, and PGE2 protein in endometriotic tissue of different groups. (a) The relative expression level of COX-1, COX-2, PGE2, and EP2 protein was detected by immunohistochemical staining (×200); the scale bar represents 50 microns. (b) The relative expression level of COX-1, COX-2, and mPGEs protein was detected by western blot. Data are expressed as mean ± standard deviation from triplicate experiments. (c) The relative expression level of COX-1, COX-2, and EP2 mRNA was detected by RT-PCR (∗P < 0.05, ∗∗P < 0.01, ∗∗∗P < 0.001, and ∗∗∗∗P < 0.0001).

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