产品: ALPPL2 抗体
货号: DF9033
描述: Rabbit polyclonal antibody to ALPPL2
应用: WB IHC IF/ICC
反应: Human
分子量: 57 kDa; 57kD(Calculated).
蛋白号: P10696
RRID: AB_2842229

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 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

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产品描述

来源:
Rabbit
应用:
IF/ICC 1:100-1:500, IHC 1:50-1:200, WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human
克隆:
Polyclonal
特异性:
ALPPL2 Antibody detects endogenous levels of total ALPPL2.
RRID:
AB_2842229
引用格式: Affinity Biosciences Cat# DF9033, RRID:AB_2842229.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

Akp5; Alkaline phosphatase; Alkaline phosphatase Nagao isozyme; Alkaline phosphatase placental like; ALP 1; ALP-1; ALP1; ALPG; ALPPL 2; ALPPL; ALPPL2; C77216; D1Ertd816e; GCAP; Germ cell alkaline phosphatase; Nagao isozyme; Placental alkaline phosphatase-like; Placental like alkaline phosphatase; placental-like; PLAP like; PLAP-like; PPBN_HUMAN; Testicular and thymus alkaline phosphatase;

抗原和靶标

免疫原:
Uniprot:
基因/基因ID:
表达:
P10696 PPBN_HUMAN:

Trace amounts in the testis and thymus, and in elevated amounts in germ cell tumors.

序列:
MQGPWVLLLLGLRLQLSLGIIPVEEENPDFWNRQAAEALGAAKKLQPAQTAAKNLIIFLGDGMGVSTVTAARILKGQKKDKLGPETFLAMDRFPYVALSKTYSVDKHVPDSGATATAYLCGVKGNFQTIGLSAAARFNQCNTTRGNEVISVMNRAKKAGKSVGVVTTTRVQHASPAGAYAHTVNRNWYSDADVPASARQEGCQDIATQLISNMDIDVILGGGRKYMFPMGTPDPEYPDDYSQGGTRLDGKNLVQEWLAKHQGARYVWNRTELLQASLDPSVTHLMGLFEPGDMKYEIHRDSTLDPSLMEMTEAALLLLSRNPRGFFLFVEGGRIDHGHHESRAYRALTETIMFDDAIERAGQLTSEEDTLSLVTADHSHVFSFGGYPLRGSSIFGLAPGKARDRKAYTVLLYGNGPGYVLKDGARPDVTESESGSPEYRQQSAVPLDGETHAGEDVAVFARGPQAHLVHGVQEQTFIAHVMAFAACLEPYTACDLAPRAGTTDAAHPGPSVVPALLPLLAGTLLLLGTATAP

翻译修饰 - P10696 作为底物

Site PTM Type Enzyme
K44 Ubiquitination
T50 Phosphorylation
K53 Ubiquitination
S111 Phosphorylation
T114 Phosphorylation
K123 Ubiquitination
K160 Ubiquitination
Y188 Phosphorylation
S196 Phosphorylation
Y225 Phosphorylation
T231 Phosphorylation
Y236 Phosphorylation
Y240 Phosphorylation
S241 Phosphorylation
K250 Ubiquitination
T364 Phosphorylation
S365 Phosphorylation
T369 Phosphorylation
T374 Phosphorylation
K400 Ubiquitination
K405 Ubiquitination
Y407 Phosphorylation
T408 Phosphorylation
Y412 Phosphorylation
Y418 Phosphorylation
K421 Ubiquitination
T429 Phosphorylation
S431 Phosphorylation
S433 Phosphorylation
S435 Phosphorylation
Y438 Phosphorylation

研究背景

细胞定位:

Cell membrane>Lipid-anchor.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Trace amounts in the testis and thymus, and in elevated amounts in germ cell tumors.

亚基结构:

Homodimer.

蛋白家族:

Belongs to the alkaline phosphatase family.

研究领域

· Metabolism > Metabolism of cofactors and vitamins > Thiamine metabolism.

· Metabolism > Metabolism of cofactors and vitamins > Folate biosynthesis.

· Metabolism > Global and overview maps > Metabolic pathways.

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