EDC4 Antibody - #DF9501

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产品: EDC4 抗体
货号: DF9501
描述: Rabbit polyclonal antibody to EDC4
应用: WB
反应: Human, Mouse, Rat
预测: Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog
分子量: 152 kDa; 152kD(Calculated).
蛋白号: Q6P2E9
RRID: AB_2842697

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   规格 价格 库存
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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产品描述

来源:
Rabbit
应用:
WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse,Rat
预测:
Pig(100%), Zebrafish(82%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(100%), Dog(100%)
克隆:
Polyclonal
特异性:
EDC4 Antibody detects endogenous levels of total EDC4.
RRID:
AB_2842697
引用格式: Affinity Biosciences Cat# DF9501, RRID:AB_2842697.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

autoantigen; Autoantigen Ge 1; Autoantigen Ge-1; Autoantigen Ge1; Autoantigen RCD 8; Autoantigen RCD-8; Autoantigen RCD8; edc4; EDC4_HUMAN; Enhancer of mRNA decapping 4; Enhancer of mRNA-decapping protein 4; Ge 1; Hedls; Human enhancer of decapping large subunit; RCD 8;

抗原和靶标

免疫原:
Uniprot:

Q6P2E9(EDC4_HUMAN) >>Visit HPA database.

基因/基因ID:
EDC4(23644)
序列:
MASCASIDIEDATQHLRDILKLDRPAGGPSAESPRPSSAYNGDLNGLLVPDPLCSGDSTSANKTGLRTMPPINLQEKQVICLSGDDSSTCIGILAKEVEIVASSDSSISSKARGSNKVKIQPVAKYDWEQKYYYGNLIAVSNSFLAYAIRAANNGSAMVRVISVSTSERTLLKGFTGSVADLAFAHLNSPQLACLDEAGNLFVWRLALVNGKIQEEILVHIRQPEGTPLNHFRRIIWCPFIPEESEDCCEESSPTVALLHEDRAEVWDLDMLRSSHSTWPVDVSQIKQGFIVVKGHSTCLSEGALSPDGTVLATASHDGYVKFWQIYIEGQDEPRCLHEWKPHDGRPLSCLLFCDNHKKQDPDVPFWRFLITGADQNRELKMWCTVSWTCLQTIRFSPDIFSSVSVPPSLKVCLDLSAEYLILSDVQRKVLYVMELLQNQEEGHACFSSISEFLLTHPVLSFGIQVVSRCRLRHTEVLPAEEENDSLGADGTHGAGAMESAAGVLIKLFCVHTKALQDVQIRFQPQLNPDVVAPLPTHTAHEDFTFGESRPELGSEGLGSAAHGSQPDLRRIVELPAPADFLSLSSETKPKLMTPDAFMTPSASLQQITASPSSSSSGSSSSSSSSSSSLTAVSAMSSTSAVDPSLTRPPEELTLSPKLQLDGSLTMSSSGSLQASPRGLLPGLLPAPADKLTPKGPGQVPTATSALSLELQEVEPLGLPQASPSRTRSPDVISSASTALSQDIPEIASEALSRGFGSSAPEGLEPDSMASAASALHLLSPRPRPGPELGPQLGLDGGPGDGDRHNTPSLLEAALTQEASTPDSQVWPTAPDITRETCSTLAESPRNGLQEKHKSLAFHRPPYHLLQQRDSQDASAEQSDHDDEVASLASASGGFGTKVPAPRLPAKDWKTKGSPRTSPKLKRKSKKDDGDAAMGSRLTEHQVAEPPEDWPALIWQQQRELAELRHSQEELLQRLCTQLEGLQSTVTGHVERALETRHEQEQRRLERALAEGQQRGGQLQEQLTQQLSQALSSAVAGRLERSIRDEIKKTVPPCVSRSLEPMAGQLSNSVATKLTAVEGSMKENISKLLKSKNLTDAIARAAADTLQGPMQAAYREAFQSVVLPAFEKSCQAMFQQINDSFRLGTQEYLQQLESHMKSRKAREQEAREPVLAQLRGLVSTLQSATEQMAATVAGSVRAEVQHQLHVAVGSLQESILAQVQRIVKGEVSVALKEQQAAVTSSIMQAMRSAAGTPVPSAHLDCQAQQAHILQLLQQGHLNQAFQQALTAADLNLVLYVCETVDPAQVFGQPPCPLSQPVLLSLIQQLASDLGTRTDLKLSYLEEAVMHLDHSDPITRDHMGSVMAQVRQKLFQFLQAEPHNSLGKAARRLSLMLHGLVTPSLP

种属预测

种属预测:

score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Rabbit
100
Zebrafish
82
Chicken
73
Xenopus
55
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - Q6P2E9 作为底物

Site PTM Type Enzyme
A2 Acetylation
S3 Phosphorylation
S6 Phosphorylation
K21 Ubiquitination
S30 Phosphorylation
S33 Phosphorylation
S37 Phosphorylation
K63 Ubiquitination
S104 Phosphorylation
S106 Phosphorylation
S107 Phosphorylation
S110 Phosphorylation
K111 Ubiquitination
K119 Ubiquitination
K125 Acetylation
K125 Ubiquitination
K287 Ubiquitination
K359 Ubiquitination
S486 Phosphorylation
S555 Phosphorylation
S560 Phosphorylation
S565 Phosphorylation
S583 Phosphorylation
S585 Phosphorylation
S586 Phosphorylation
T588 Phosphorylation
S613 Phosphorylation
S621 Phosphorylation
S622 Phosphorylation
S623 Phosphorylation
S624 Phosphorylation
S664 Phosphorylation
S676 Phosphorylation
T693 Phosphorylation
S708 Phosphorylation
S723 Phosphorylation
S725 Phosphorylation
T727 Phosphorylation
S729 Phosphorylation
S734 Phosphorylation
S735 Phosphorylation
S737 Phosphorylation
T738 Phosphorylation
S741 Phosphorylation
S780 Phosphorylation
T807 Phosphorylation
S809 Phosphorylation
S820 Phosphorylation
T821 Phosphorylation
S824 Phosphorylation
T837 Phosphorylation
S844 Phosphorylation
S855 Phosphorylation
Y863 Phosphorylation
S871 Phosphorylation
S875 Phosphorylation
S879 Phosphorylation
S887 Phosphorylation
S892 Phosphorylation
T911 Phosphorylation
S914 Phosphorylation
S918 Phosphorylation
R965 Methylation
S967 Phosphorylation
R1015 Methylation
T1050 Phosphorylation
C1054 S-Nitrosylation
S1058 Phosphorylation
S1067 Phosphorylation
T1072 Phosphorylation
T1075 Phosphorylation
S1080 Phosphorylation
K1082 Ubiquitination
K1087 Ubiquitination
K1092 Ubiquitination
Y1148 Phosphorylation
S1154 Phosphorylation
K1157 Ubiquitination
K1368 Ubiquitination
S1380 Phosphorylation
K1383 Ubiquitination
S1389 Phosphorylation
S1399 Phosphorylation

研究背景

功能:

In the process of mRNA degradation, seems to play a role in mRNA decapping. Component of a complex containing DCP2 and DCP1A which functions in decapping of ARE-containing mRNAs. Promotes complex formation between DCP1A and DCP2. Enhances the catalytic activity of DCP2 (in vitro).

细胞定位:

Cytoplasm>P-body. Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
亚基结构:

Part of a decapping complex consisting of DCP1A, DCP2, EDC3, EDC4 and probably DDX6. Part of a complex consisting of DCP1A, EDC3, EDC4 and DDX6. Part of a complex consisting of DCP1B, EDC3, EDC4 and DDX6. Interacts with DCP2. Interacts with RC3H1 (By similarity). Interacts with NBDY. Interacts with TEX19 (By similarity).

蛋白家族:

Belongs to the WD repeat EDC4 family.

研究领域

· Genetic Information Processing > Folding, sorting and degradation > RNA degradation.

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