| 产品: | PTGDS2 抗体 |
| 货号: | DF9534 |
| 描述: | Rabbit polyclonal antibody to PTGDS2 |
| 应用: | WB |
| 反应: | Human |
| 预测: | Bovine, Horse, Sheep, Rabbit, Dog |
| 分子量: | 23 kDa; 23kD(Calculated). |
| 蛋白号: | O60760 |
| RRID: | AB_2842730 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF9534, RRID:AB_2842730.
展开/折叠
Cerebrin 28; Glutathione dependent PGD synthetase; Glutathione S-transferase; Glutathione-dependent PGD synthase; Glutathione-requiring prostaglandin D synthase; GST class-sigma; H PGDS; H-PGDS; Haematopoietic prostaglandin D synthase; Haematopoietic prostaglandin D2 synthase; Hematopoietic prostaglandin D synthase; Hpgds; HPGDS_HUMAN; Prostaglandin D synthase; Prostaglandin D2 synthase hematopoietic; Prostaglandin H2 D isomerase; Prostaglandin-H2 D-isomerase; PTGDS2;
抗原和靶标
Expressed in a number of megakaryocytic cell lines but not in platelets. Highly expressed in adipose tissue, macrophages and placenta. Also expressed at lower levels in lung, heart, lymph nodes, appendix, bone marrow and fetal liver.
- O60760 HPGDS_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MPNYKLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQADWPEIKSTLPFGKIPILEVDGLTLHQSLAIARYLTKNTDLAGNTEMEQCHVDAIVDTLDDFMSCFPWAEKKQDVKEQMFNELLTYNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDLLDNHPRLVTLRKKVQAIPAVANWIKRRPQTKL
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
研究背景
Bifunctional enzyme which catalyzes both the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation, and the conjugation of glutathione with a wide range of aryl halides and organic isothiocyanates. Also exhibits low glutathione-peroxidase activity towards cumene hydroperoxide.
Cytoplasm.
Expressed in a number of megakaryocytic cell lines but not in platelets. Highly expressed in adipose tissue, macrophages and placenta. Also expressed at lower levels in lung, heart, lymph nodes, appendix, bone marrow and fetal liver.
Homodimer.
Belongs to the GST superfamily. Sigma family.
研究领域
· Human Diseases > Cancers: Overview > Chemical carcinogenesis.
· Metabolism > Metabolism of other amino acids > Glutathione metabolism.
· Metabolism > Lipid metabolism > Arachidonic acid metabolism.
· Metabolism > Xenobiotics biodegradation and metabolism > Metabolism of xenobiotics by cytochrome P450.
· Metabolism > Xenobiotics biodegradation and metabolism > Drug metabolism - cytochrome P450.
· Metabolism > Global and overview maps > Metabolic pathways.
限制条款
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