| 产品: | CD42c/GP1BB 抗体 |
| 货号: | DF9759 |
| 描述: | Rabbit polyclonal antibody to CD42c/GP1BB |
| 应用: | WB IHC |
| 反应: | Human, Mouse, Monkey |
| 预测: | Bovine, Dog |
| 分子量: | 22 kDa; 22kD(Calculated). |
| 蛋白号: | P13224 |
| RRID: | AB_2842954 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF9759, RRID:AB_2842954.
展开/折叠
Antigen CD42b beta; BDPLT1; BS; CD_antigen=CD42c; Flags: Precursor; Glycoprotein Ib (platelet) beta polypeptide; Glycoprotein Ib beta polypeptide; GP Ib beta; GP Ib beta subunit; GP1BB; GP1bbeta; GPIb beta; Nuclear localization signal deleted in velocardiofacial syndrome; Platelet glycoprotein Ib beta chain; Platelet glycoprotein Ib beta polypeptide;
抗原和靶标
- P13224 GP1BB_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGSGPRGALSLLLLLLAPPSRPAAGCPAPCSCAGTLVDCGRRGLTWASLPTAFPVDTTELVLTGNNLTALPPGLLDALPALRTAHLGANPWRCDCRLVPLRAWLAGRPERAPYRDLRCVAPPALRGRLLPYLAEDELRAACAPGPLCWGALAAQLALLGLGLLHALLLVLLLCRLRRLRARARARAAARLSLTDPLVAERAGTDES
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P13224 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| N66 | N-Glycosylation | Uniprot | |
| T83 | O-Glycosylation | Uniprot | |
| S191 | Phosphorylation | Uniprot | |
| T193 | Phosphorylation | Uniprot | |
| T203 | Phosphorylation | Uniprot |
研究背景
Gp-Ib, a surface membrane protein of platelets, participates in the formation of platelet plugs by binding to von Willebrand factor, which is already bound to the subendothelium.
Membrane>Single-pass type I membrane protein.
Expressed in heart and brain.
Two GP-Ib beta are disulfide-linked to one GP-Ib alpha. GP-IX is complexed with the GP-Ib heterodimer via a non covalent linkage.
研究领域
· Environmental Information Processing > Signaling molecules and interaction > ECM-receptor interaction. (View pathway)
· Organismal Systems > Immune system > Platelet activation. (View pathway)
· Organismal Systems > Immune system > Hematopoietic cell lineage. (View pathway)
限制条款
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