产品: PABPC3 抗体
货号: DF9761
描述: Rabbit polyclonal antibody to PABPC3
应用: WB IHC IF/ICC
反应: Human, Mouse, Monkey
分子量: 70 kDa; 70kD(Calculated).
蛋白号: Q9H361
RRID: AB_2842956

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   规格 价格 库存
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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产品描述

来源:
Rabbit
应用:
WB 1:1000-3000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse,Monkey
克隆:
Polyclonal
特异性:
PABPC3 Antibody detects endogenous levels of total PABPC3.
RRID:
AB_2842956
引用格式: Affinity Biosciences Cat# DF9761, RRID:AB_2842956.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

PABP-3; PABP3; PABP3_HUMAN; PABPC3; PABPL3; Poly(A) binding protein 3; Poly(A)-binding protein 3; Polyadenylate binding protein 3; Polyadenylate-binding protein 3; RP11-165I9.5; Testis specific poly(A) binding protein; Testis-specific poly(A)-binding protein; tPABP;

抗原和靶标

免疫原:
Uniprot:
基因/基因ID:
表达:
Q9H361 PABP3_HUMAN:

Testis specific.

序列:
MNPSTPSYPTASLYVGDLHPDVTEAMLYEKFSPAGPILSIRICRDLITSGSSNYAYVNFQHTKDAEHALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFVKNLDKSINNKALYDTVSAFGNILSCNVVCDENGSKGYGFVHFETHEAAERAIKKMNGMLLNGRKVFVGQFKSRKEREAELGARAKEFPNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRTFEQMKQDRITRYQVVNLYVKNLDDGIDDERLRKAFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQRKEERQAYLTNEYMQRMASVRAVPNQRAPPSGYFMTAVPQTQNHAAYYPPSQIARLRPSPRWTAQGARPHPFQNKPSAIRPGAPRVPFSTMRPASSQVPRVMSTQRVANTSTQTVGPRPAAAAAAAATPAVRTVPRYKYAAGVRNPQQHRNAQPQVTMQQLAVHVQGQETLTASRLASAPPQKQKQMLGERLFPLIQAMHPTLAGKITGMLLEIDNSELLYMLESPESLRSKVDEAVAVLQAHQAKEATQKAVNSATGVPTV

翻译修饰 - Q9H361 作为底物

Site PTM Type Enzyme
S32 Phosphorylation
Y56 Phosphorylation
T71 Phosphorylation
K78 Ubiquitination
K80 Ubiquitination
S92 Phosphorylation
K108 Ubiquitination
K188 Methylation
Y194 Phosphorylation
K208 Ubiquitination
K213 Acetylation
K213 Ubiquitination
S219 Phosphorylation
K221 Ubiquitination
T224 Phosphorylation
K229 Ubiquitination
S230 Phosphorylation
K231 Ubiquitination
S237 Phosphorylation
R240 Methylation
K246 Ubiquitination
K254 Ubiquitination
K259 Acetylation
K259 Ubiquitination
Y262 Phosphorylation
K269 Ubiquitination
K284 Ubiquitination
R309 Methylation
S315 Phosphorylation
K333 Ubiquitination
S341 Phosphorylation
S342 Phosphorylation
K348 Ubiquitination
T360 Phosphorylation
K361 Ubiquitination
Y364 Phosphorylation
R426 Methylation
R430 Methylation
R437 Methylation
S458 Phosphorylation
T459 Phosphorylation
R461 Methylation
R469 Methylation
S480 Phosphorylation
K601 Ubiquitination
T630 Phosphorylation

研究背景

功能:

Binds the poly(A) tail of mRNA. May be involved in cytoplasmic regulatory processes of mRNA metabolism. Binds poly(A) with a slightly lower affinity as compared to PABPC1.

细胞定位:

Cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Testis specific.

蛋白家族:

Belongs to the polyadenylate-binding protein type-1 family.

研究领域

· Genetic Information Processing > Translation > RNA transport.

· Genetic Information Processing > Translation > mRNA surveillance pathway.

· Genetic Information Processing > Folding, sorting and degradation > RNA degradation.

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