STX6 Antibody - #DF9956

(4)  
产品: STX6 抗体
货号: DF9956
描述: Rabbit polyclonal antibody to STX6
应用: WB IHC IF/ICC
反应: Human, Mouse, Rat
预测: Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus
分子量: 29 kDa; 29kD(Calculated).
蛋白号: O43752
RRID: AB_2843150

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 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

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产品描述

来源:
Rabbit
应用:
WB 1:1000-3000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse,Rat
预测:
Pig(100%), Zebrafish(83%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(100%), Dog(100%), Chicken(100%), Xenopus(83%)
克隆:
Polyclonal
特异性:
STX6 Antibody detects endogenous levels of total STX6.
RRID:
AB_2843150
引用格式: Affinity Biosciences Cat# DF9956, RRID:AB_2843150.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

STX 6; STX6; STX-6; STX6_HUMAN; Syntaxin-6; Syntaxin6;

抗原和靶标

免疫原:
Uniprot:

O43752(STX6_HUMAN) >>Visit HPA database.

基因/基因ID:
STX6(10228)
序列:
MSMEDPFFVVKGEVQKAVNTAQGLFQRWTELLQDPSTATREEIDWTTNELRNNLRSIEWDLEDLDETISIVEANPRKFNLDATELSIRKAFITSTRQVVRDMKDQMSTSSVQALAERKNRQALLGDSGSQNWSTGTTDKYGRLDRELQRANSHFIEEQQAQQQLIVEQQDEQLELVSGSIGVLKNMSQRIGGELEEQAVMLEDFSHELESTQSRLDNVMKKLAKVSHMTSDRRQWCAIAILFAVLLVVLILFLVL

种属预测

种属预测:

score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Chicken
100
Rabbit
100
Xenopus
83
Zebrafish
83
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - O43752 作为底物

Site PTM Type Enzyme
S2 Acetylation
S2 Phosphorylation
K77 Ubiquitination
T83 Phosphorylation
S86 Phosphorylation
K89 Ubiquitination
S107 Phosphorylation
K118 Ubiquitination
S127 Phosphorylation
S129 Phosphorylation
T134 Phosphorylation
T137 Phosphorylation
K139 Ubiquitination
Y140 Phosphorylation
S152 Phosphorylation
K184 Ubiquitination
T229 Phosphorylation
S230 Phosphorylation

研究背景

功能:

Involved in intracellular vesicle trafficking.

细胞定位:

Golgi apparatus membrane>Single-pass type IV membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
亚基结构:

Identified in a complex containing STX6, STX12, VAMP4 and VTI1A. Binds EEA1 (By similarity). Interacts with VPS45A (By similarity). Interacts with MARCHF2 and MARCHF3 (By similarity). Interacts with GOPC. Interacts with UHRF1BP1L (via C-terminal coiled-coil domain). Interacts with BAIAP3; this interaction is increased in the presence of calcium.

蛋白家族:

Belongs to the syntaxin family.

研究领域

· Genetic Information Processing > Folding, sorting and degradation > SNARE interactions in vesicular transport.

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