Syntaxin3 Antibody - #DF12760

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产品: Syntaxin3 抗体
货号: DF12760
描述: Rabbit polyclonal antibody to Syntaxin3
应用: WB
反应: Human, Mouse, Rat
预测: Pig, Bovine, Horse, Rabbit, Dog, Chicken
分子量: 33 kDa; 33kD(Calculated).
蛋白号: Q13277
RRID: AB_2845721

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产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse,Rat
预测:
Pig(100%), Bovine(100%), Horse(100%), Rabbit(86%), Dog(100%), Chicken(82%)
克隆:
Polyclonal
特异性:
Syntaxin3 Antibody detects endogenous levels of total Syntaxin3.
RRID:
AB_2845721
引用格式: Affinity Biosciences Cat# DF12760, RRID:AB_2845721.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

FLJ30906; Stx3; STX3_HUMAN; STX3A; Syntaxin 3A; Syntaxin-3;

抗原和靶标

免疫原:
Uniprot:

Q13277(STX3_HUMAN) >>Visit HPA database.

基因/基因ID:
STX3(6809)
序列:
MKDRLEQLKAKQLTQDDDTDAVEIAIDNTAFMDEFFSEIEETRLNIDKISEHVEEAKKLYSIILSAPIPEPKTKDDLEQLTTEIKKRANNVRNKLKSMEKHIEEDEVRSSADLRIRKSQHSVLSRKFVEVMTKYNEAQVDFRERSKGRIQRQLEITGKKTTDEELEEMLESGNPAIFTSGIIDSQISKQALSEIEGRHKDIVRLESSIKELHDMFMDIAMLVENQGEMLDNIELNVMHTVDHVEKARDETKKAVKYQSQARKKLIIIIVLVVVLLGILALIIGLSVGLN

种属预测

种属预测:

score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Dog
100
Rabbit
86
Chicken
82
Sheep
73
Xenopus
73
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - Q13277 作为底物

Site PTM Type Enzyme
K9 Ubiquitination
T14 Phosphorylation
K100 Ubiquitination
K117 Ubiquitination
K126 Ubiquitination
K159 Ubiquitination
K188 Ubiquitination
S192 Phosphorylation
S206 Phosphorylation
S207 Phosphorylation

研究背景

功能:

Potentially involved in docking of synaptic vesicles at presynaptic active zones.

细胞定位:

Membrane>Single-pass type IV membrane protein.
Note: Localized to the inner and outer plexiform layers, the cell body and the inner segments of photoreceptors.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
亚基结构:

Interacts with REEP6 (By similarity). Interacts with PRPH2 in rod and cone photoreceptors (By similarity). Interacts with ROM1 (By similarity). Interacts with SNAP25 (By similarity). Interacts with VAMP2 (By similarity).

蛋白家族:

Belongs to the syntaxin family.

研究领域

· Genetic Information Processing > Folding, sorting and degradation > SNARE interactions in vesicular transport.

· Organismal Systems > Nervous system > Synaptic vesicle cycle.

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