FUT6 Antibody - #DF13025

(4)  
产品: FUT6 抗体
货号: DF13025
描述: Rabbit polyclonal antibody to FUT6
应用: WB IHC IF/ICC
反应: Human, Mouse
分子量: 45 kDa; 42kD(Calculated).
蛋白号: P51993
RRID: AB_2845986

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 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

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WB Handbook
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IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000, IF/ICC 1:100-1:500, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse
克隆:
Polyclonal
特异性:
FUT6 Antibody detects endogenous levels of total FUT6.
RRID:
AB_2845986
引用格式: Affinity Biosciences Cat# DF13025, RRID:AB_2845986.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

Alpha (1,3) fucosyltransferase; EC=2.4.1.65; FCT3A; FT1A; Fuc TVI; fucosyltransferase 6 (alpha (1,3) fucosyltransferase); Fucosyltransferase 6; Fucosyltransferase VI; FucT VI; Galactoside 3 L fucosyltransferase;

抗原和靶标

免疫原:
Uniprot:

P51993(FUT6_HUMAN) >>Visit HPA database.

基因/基因ID:
FUT6(2528)
表达:
P51993 FUT6_HUMAN:

Kidney, liver, colon, small intestine, bladder, uterus and salivary gland.

序列:
MDPLGPAKPQWSWRCCLTTLLFQLLMAVCFFSYLRVSQDDPTVYPNGSRFPDSTGTPAHSIPLILLWTWPFNKPIALPRCSEMVPGTADCNITADRKVYPQADAVIVHHREVMYNPSAQLPRSPRRQGQRWIWFSMESPSHCWQLKAMDGYFNLTMSYRSDSDIFTPYGWLEPWSGQPAHPPLNLSAKTELVAWAVSNWGPNSARVRYYQSLQAHLKVDVYGRSHKPLPQGTMMETLSRYKFYLAFENSLHPDYITEKLWRNALEAWAVPVVLGPSRSNYERFLPPDAFIHVDDFQSPKDLARYLQELDKDHARYLSYFRWRETLRPRSFSWALAFCKACWKLQEESRYQTRGIAAWFT

翻译修饰 - P51993 作为底物

Site PTM Type Enzyme
S123 Phosphorylation
Y208 Phosphorylation
Y209 Phosphorylation
Y221 Phosphorylation
Y315 Phosphorylation
T324 Phosphorylation

研究背景

功能:

Enzyme involved in the biosynthesis of the E-Selectin ligand, sialyl-Lewis X. Catalyzes the transfer of fucose from GDP-beta-fucose to alpha-2,3 sialylated substrates.

细胞定位:

Golgi apparatus>Golgi stack membrane>Single-pass type II membrane protein.
Note: Membrane-bound form in trans cisternae of Golgi.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Kidney, liver, colon, small intestine, bladder, uterus and salivary gland.

蛋白家族:

Belongs to the glycosyltransferase 10 family.

研究领域

· Metabolism > Glycan biosynthesis and metabolism > Glycosphingolipid biosynthesis - lacto and neolacto series.

· Metabolism > Global and overview maps > Metabolic pathways.

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