PSMD1 Antibody - #DF13463

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产品: PSMD1 抗体
货号: DF13463
描述: Rabbit polyclonal antibody to PSMD1
应用: WB IHC
反应: Human, Mouse, Rat
预测: Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus
分子量: 105kDa; 106kD(Calculated).
蛋白号: Q99460
RRID: AB_2846482

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   规格 价格 库存
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

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相关下载
MS Report
HPLC Report
MSDS
说明书
COA
实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse,Rat
预测:
Pig(100%), Zebrafish(100%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(100%), Dog(100%), Chicken(100%), Xenopus(100%)
克隆:
Polyclonal
特异性:
PSMD1 Antibody detects endogenous levels of total PSMD1.
RRID:
AB_2846482
引用格式: Affinity Biosciences Cat# DF13463, RRID:AB_2846482.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

;MGC133041; 26S proteasome non ATPase regulatory subunit 1; 26S proteasome non ATPase subunit 1; 26S proteasome non-ATPase regulatory subunit 1; 26S proteasome regulatory subunit rpn2; 26S proteasome regulatory subunit S1; 26S proteasome subunit p112; MGC133040; P112; Proteasome (prosome macropain) 26S subunit, non ATPase 1; Psmd1; PSMD1_HUMAN; RPN2; S1;

抗原和靶标

免疫原:
Uniprot:

Q99460(PSMD1_HUMAN) >>Visit HPA database.

基因/基因ID:
PSMD1(5707)
序列:
MITSAAGIISLLDEDEPQLKEFALHKLNAVVNDFWAEISESVDKIEVLYEDEGFRSRQFAALVASKVFYHLGAFEESLNYALGAGDLFNVNDNSEYVETIIAKCIDHYTKQCVENADLPEGEKKPIDQRLEGIVNKMFQRCLDDHKYKQAIGIALETRRLDVFEKTILESNDVPGMLAYSLKLCMSLMQNKQFRNKVLRVLVKIYMNLEKPDFINVCQCLIFLDDPQAVSDILEKLVKEDNLLMAYQICFDLYESASQQFLSSVIQNLRTVGTPIASVPGSTNTGTVPGSEKDSDSMETEEKTSSAFVGKTPEASPEPKDQTLKMIKILSGEMAIELHLQFLIRNNNTDLMILKNTKDAVRNSVCHTATVIANSFMHCGTTSDQFLRDNLEWLARATNWAKFTATASLGVIHKGHEKEALQLMATYLPKDTSPGSAYQEGGGLYALGLIHANHGGDIIDYLLNQLKNASNDIVRHGGSLGLGLAAMGTARQDVYDLLKTNLYQDDAVTGEAAGLALGLVMLGSKNAQAIEDMVGYAQETQHEKILRGLAVGIALVMYGRMEEADALIESLCRDKDPILRRSGMYTVAMAYCGSGNNKAIRRLLHVAVSDVNDDVRRAAVESLGFILFRTPEQCPSVVSLLSESYNPHVRYGAAMALGICCAGTGNKEAINLLEPMTNDPVNYVRQGALIASALIMIQQTEITCPKVNQFRQLYSKVINDKHDDVMAKFGAILAQGILDAGGHNVTISLQSRTGHTHMPSVVGVLVFTQFWFWFPLSHFLSLAYTPTCVIGLNKDLKMPKVQYKSNCKPSTFAYPAPLEVPKEKEKEKVSTAVLSITAKAKKKEKEKEKKEEEKMEVDEAEKKEEKEKKKEPEPNFQLLDNPARVMPAQLKVLTMPETCRYQPFKPLSIGGIIILKDTSEDIEELVEPVAAHGPKIEEEEQEPEPPEPFEYIDD

种属预测

种属预测:

score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Xenopus
100
Zebrafish
100
Chicken
100
Rabbit
100
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - Q99460 作为底物

Site PTM Type Enzyme
M1 Acetylation
K20 Ubiquitination
K26 Ubiquitination
Y49 Phosphorylation
K110 Ubiquitination
K124 Ubiquitination
K136 Ubiquitination
K146 Ubiquitination
Y147 Phosphorylation
T157 Phosphorylation
K191 Ubiquitination
R199 Methylation
T270 Phosphorylation
T273 Phosphorylation Q16539 (MAPK14)
S277 Phosphorylation
S281 Phosphorylation
T284 Phosphorylation
S290 Phosphorylation
K292 Ubiquitination
S294 Phosphorylation
S296 Phosphorylation
T299 Phosphorylation
K302 Ubiquitination
T303 Phosphorylation
S305 Phosphorylation
K310 Acetylation
K310 Sumoylation
K310 Ubiquitination
T311 Phosphorylation
S315 Phosphorylation
K319 Ubiquitination
K324 Ubiquitination
T348 Phosphorylation
K354 Ubiquitination
K401 Acetylation
K413 Acetylation
K417 Acetylation
K417 Ubiquitination
T488 Phosphorylation
Y494 Phosphorylation
K543 Ubiquitination
K574 Ubiquitination
K597 Ubiquitination
S608 Phosphorylation
Y713 Phosphorylation
K715 Ubiquitination
K720 Acetylation
K720 Ubiquitination
K799 Ubiquitination
K803 Ubiquitination
K807 Ubiquitination
Y813 Phosphorylation
K821 Ubiquitination
K825 Ubiquitination
K827 Ubiquitination
T830 Phosphorylation
S834 Phosphorylation
K838 Ubiquitination
K840 Ubiquitination
K849 Acetylation
K853 Ubiquitination
K861 Ubiquitination
K862 Ubiquitination
K865 Ubiquitination
K868 Ubiquitination
K869 Ubiquitination
K890 Ubiquitination
Y900 Phosphorylation
K904 Ubiquitination
K915 Ubiquitination
K934 Sumoylation
K934 Ubiquitination
Y950 Phosphorylation

研究背景

功能:

Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.

亚基结构:

Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP). The regulatory particle is made of a lid composed of 9 subunits, a base containing 6 ATPases and few additional components including PSMD1. Interacts with ADRM1. Interacts with ZFAND1.

蛋白家族:

Belongs to the proteasome subunit S1 family.

研究领域

· Genetic Information Processing > Folding, sorting and degradation > Proteasome.

· Human Diseases > Infectious diseases: Viral > Epstein-Barr virus infection.

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