PLA2G10 Antibody - #DF14565

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产品: PLA2G10 抗体
货号: DF14565
描述: Rabbit polyclonal antibody to PLA2G10
应用: IF/ICC
反应: Human, Mouse, Rat
分子量: 18kD(Calculated).
蛋白号: O15496

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 100ul RMB¥ 2300 现货
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IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse,Rat
克隆:
Polyclonal
特异性:
PLA2G10 Antibody detects endogenous levels of PLA2G10.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

Group 10 secretory phospholipase A2; Group X secretory phospholipase A2; GX sPLA2; GXPLA2; GXSPLA2; PA2GX_HUMAN; Phosphatidylcholine 2 acylhydrolase GX; Phosphatidylcholine 2-acylhydrolase 10; Phospholipase A2 group X; PLA2G10; SPLA2; sPLA2-X; sPLA2X;

抗原和靶标

免疫原:

A synthesized peptide derived from human PLA2G10.

Uniprot:

O15496(PA2GX_HUMAN) >>Visit HPA database.

基因/基因ID:
PLA2G10(8399)
表达:
O15496 PA2GX_HUMAN:

Found in spleen, thymus, peripheral blood leukocytes, pancreas, lung, and colon.

序列:
MGPLPVCLPIMLLLLLPSLLLLLLLPGPGSGEASRILRVHRRGILELAGTVGCVGPRTPIAYMKYGCFCGLGGHGQPRDAIDWCCHGHDCCYTRAEEAGCSPKTERYSWQCVNQSVLCGPAENKCQELLCKCDQEIANCLAQTEYNLKYLFYPQFLCEPDSPKCD

研究背景

功能:

PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. Has a powerful potency for releasing arachidonic acid from cell membrane phospholipids. Prefers phosphatidylethanolamine and phosphatidylcholine liposomes to those of phosphatidylserine.

细胞定位:

Secreted.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Found in spleen, thymus, peripheral blood leukocytes, pancreas, lung, and colon.

蛋白家族:

Belongs to the phospholipase A2 family.

研究领域

· Environmental Information Processing > Signal transduction > Ras signaling pathway.   (View pathway)

· Metabolism > Lipid metabolism > Glycerophospholipid metabolism.

· Metabolism > Lipid metabolism > Ether lipid metabolism.

· Metabolism > Lipid metabolism > Arachidonic acid metabolism.

· Metabolism > Lipid metabolism > Linoleic acid metabolism.

· Metabolism > Lipid metabolism > alpha-Linolenic acid metabolism.

· Metabolism > Global and overview maps > Metabolic pathways.

· Organismal Systems > Circulatory system > Vascular smooth muscle contraction.   (View pathway)

· Organismal Systems > Digestive system > Pancreatic secretion.

· Organismal Systems > Digestive system > Fat digestion and absorption.

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