T3JAM Antibody - #DF3633

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产品: T3JAM 抗体
货号: DF3633
描述: Rabbit polyclonal antibody to T3JAM
应用: WB IHC IF/ICC
反应: Human, Mouse, Rat
预测: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken
分子量: 64 KD; 64kD(Calculated).
蛋白号: Q9Y228
RRID: AB_2836005

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

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MS Report
HPLC Report
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说明书
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实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse,Rat
预测:
Pig(91%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(100%), Dog(100%), Chicken(80%)
克隆:
Polyclonal
特异性:
T3JAM Antibody detects endogenous levels of total T3JAM.
RRID:
AB_2836005
引用格式: Affinity Biosciences Cat# DF3633, RRID:AB_2836005.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

T3JAM; TRAF3 interacting JNK activating modulator; TRAF3 interacting protein 3;

抗原和靶标

免疫原:
Uniprot:

Q9Y228(T3JAM_HUMAN) >>Visit HPA database.

基因/基因ID:
TRAF3IP3(80342)
序列:
MISPDPRPSPGLARWAESYEAKCERRQEIRESRRCRPNVTTCRQVGKTLRIQQREQLQRARLQQFFRRRNLELEEKGKAQHPQAREQGPSRRPGQVTVLKEPLSCARRISSPREQVTGTSSEVFPAQHPPPSGICRDLSDHLSSQAGGLPPQDTPIKKPPKHHRGTQTKAEGPTIKNDASQQTNYGVAVLDKEIIQLSDYLKEALQRELVLKQKMVILQDLLSTLIQASDSSWKGQLNEDKLKGKLRSLENQLYTCTQKYSPWGMKKVLLEMEDQKNSYEQKAKESLQKVLEEKMNAEQQLQSTQRSLALAEQKCEEWRSQYEALKEDWRTLGTQHRELESQLHVLQSKLQGADSRDLQMNQALRFLENEHQQLQAKIECLQGDRDLCSLDTQDLQDQLKRSEAEKLTLVTRVQQLQGLLQNQSLQLQEQEKLLTKKDQALPVWSPKSFPNEVEPEGTGKEKDWDLRDQLQKKTLQLQAKEKECRELHSELDNLSDEYLSCLRKLQHCREELNQSQQLPPRRQCGRWLPVLMVVIAAALAVFLANKDNLMI

种属预测

种属预测:

score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。

Species
Results
Score
Horse
100
Bovine
100
Sheep
100
Dog
100
Rabbit
100
Pig
91
Chicken
80
Xenopus
78
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - Q9Y228 作为底物

Site PTM Type Enzyme
S3 Phosphorylation
S9 Phosphorylation
S110 Phosphorylation
S111 Phosphorylation
T154 Phosphorylation
S180 Phosphorylation
T183 Phosphorylation
Y185 Phosphorylation
K192 Ubiquitination
K202 Ubiquitination
Y254 Phosphorylation
T255 Phosphorylation
Y260 Phosphorylation
S261 Phosphorylation
K267 Ubiquitination
K276 Ubiquitination
K294 Ubiquitination
K314 Ubiquitination
Y322 Phosphorylation
K326 Ubiquitination
K349 Ubiquitination
K377 Ubiquitination
K400 Ubiquitination
K406 Ubiquitination
S445 Phosphorylation
K447 Ubiquitination
K462 Ubiquitination
K472 Ubiquitination
K473 Ubiquitination
K480 Ubiquitination

研究背景

功能:

May function as an adapter molecule that regulates TRAF3-mediated JNK activation.

细胞定位:

Membrane>Single-pass type IV membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
亚基结构:

Binds to the isoleucine zipper of TRAF3 via its coiled-coil domain.

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