ARSG Antibody - #DF3797

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产品: ARSG 抗体
货号: DF3797
描述: Rabbit polyclonal antibody to ARSG
应用: WB IHC
反应: Human, Mouse, Rat
预测: Rabbit
分子量: 65 KD; 57kD(Calculated).
蛋白号: Q96EG1
RRID: AB_2836154

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 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

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MSDS
说明书
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实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:500-1:1000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse,Rat
预测:
Rabbit(88%)
克隆:
Polyclonal
特异性:
ARSG Antibody detects endogenous levels of total ARSG.
RRID:
AB_2836154
引用格式: Affinity Biosciences Cat# DF3797, RRID:AB_2836154.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

Arsg; ARSG_HUMAN; Arylsulfatase G; Arylsulfatase G precursor; ASG; KIAA1001; PRO1777; UNQ839;

抗原和靶标

免疫原:
Uniprot:

Q96EG1(ARSG_HUMAN) >>Visit HPA database.

基因/基因ID:
ARSG(22901)
表达:
Q96EG1 ARSG_HUMAN:

Widely expressed, with very low expression in brain, lung, heart and skeletal muscle.

序列:
MGWLFLKVLLAGVSFSGFLYPLVDFCISGKTRGQKPNFVIILADDMGWGDLGANWAETKDTANLDKMASEGMRFVDFHAAASTCSPSRASLLTGRLGLRNGVTRNFAVTSVGGLPLNETTLAEVLQQAGYVTGIIGKWHLGHHGSYHPNFRGFDYYFGIPYSHDMGCTDTPGYNHPPCPACPQGDGPSRNLQRDCYTDVALPLYENLNIVEQPVNLSSLAQKYAEKATQFIQRASTSGRPFLLYVALAHMHVPLPVTQLPAAPRGRSLYGAGLWEMDSLVGQIKDKVDHTVKENTFLWFTGDNGPWAQKCELAGSVGPFTGFWQTRQGGSPAKQTTWEGGHRVPALAYWPGRVPVNVTSTALLSVLDIFPTVVALAQASLPQGRRFDGVDVSEVLFGRSQPGHRVLFHPNSGAAGEFGALQTVRLERYKAFYITGGARACDGSTGPELQHKFPLIFNLEDDTAEAVPLERGGAEYQAVLPEVRKVLADVLQDIANDNISSADYTQDPSVTPCCNPYQIACRCQAA

种属预测

种属预测:

score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。

Species
Results
Score
Rabbit
88
Pig
0
Horse
0
Bovine
0
Sheep
0
Dog
0
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - Q96EG1 作为底物

Site PTM Type Enzyme
S69 Phosphorylation
Y196 Phosphorylation
Y204 Phosphorylation
S218 Phosphorylation
K226 Ubiquitination
S379 Phosphorylation
K451 Ubiquitination

研究背景

功能:

Displays arylsulfatase activity at acidic pH with pseudosubstrates, such as p-nitrocatechol sulfate and also, but with lower activity, p-nitrophenyl sulfate and 4-methylumbelliferyl sulfate.

翻译修饰:

N-glycosylated.

The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

Glycosylated.

细胞定位:

Lysosome.
Note: Previously observed endoplasmic reticulum localization is most likely due to folding/maturation problems for overexpressed proteins.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Widely expressed, with very low expression in brain, lung, heart and skeletal muscle.

蛋白家族:

Belongs to the sulfatase family.

研究领域

· Cellular Processes > Transport and catabolism > Lysosome.   (View pathway)

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