产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF4279, RRID:AB_2836630.
展开/折叠
2-trans-enoyl-CoA isomerase; ACBD2; acyl Coenzyme A binding domain containing 2; D2-enoyl-CoA isomerase; D3; D3 D2 enoyl CoA isomerase; DBI related protein 1; DBI-related protein 1; delta(2)-enoyl-CoA isomerase; Delta(3); Delta(3) delta(2) enoyl CoA isomerase; Diazepam-binding inhibitor-related protein 1; Dodecenoyl CoA isomerase; Dodecenoyl-CoA isomerase; DRS 1; DRS-1; DRS1; Eci2; ECI2_HUMAN; Enoyl-CoA delta isomerase 2; HCA88; Hepatocellular carcinoma associated antigen 88; Hepatocellular carcinoma-associated antigen 88; mitochondrial; pECI; Peroxisomal 3; Peroxisomal 3,2-trans-enoyl-CoA isomerase; Peroxisomal D3 D2 enoyl CoA isomerase; Renal carcinoma antigen NY REN 1; Renal carcinoma antigen NY-REN-1;
抗原和靶标
Abundant in heart, skeletal muscle and liver. Expressed in CD34(+) T-cells and CD34(+) bone marrow cells.
- O75521 ECI2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAMAYLAWRLARRSCPSSLQVTSFPVVQLHMNRTAMRASQKDFENSMNQVKLLKKDPGNEVKLKLYALYKQATEGPCNMPKPGVFDLINKAKWDAWNALGSLPKEAARQNYVDLVSSLSPSLESSSQVEPGTDRKSTGFETLVVTSEDGITKIMFNRPKKKNAINTEMYHEIMRALKAASKDDSIITVLTGNGDYYSSGNDLTNFTDIPPGGVEEKAKNNAVLLREFVGCFIDFPKPLIAVVNGPAVGISVTLLGLFDAVYASDRATFHTPFSHLGQSPEGCSSYTFPKIMSPAKATEMLIFGKKLTAGEACAQGLVTEVFPDSTFQKEVWTRLKAFAKLPPNALRISKEVIRKREREKLHAVNAEECNVLQGRWLSDECTNAVVNFLSRKSKL
翻译修饰 - O75521 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S39 | Phosphorylation | Uniprot | |
| K41 | Acetylation | Uniprot | |
| K51 | Acetylation | Uniprot | |
| K54 | Acetylation | Uniprot | |
| K62 | Acetylation | Uniprot | |
| Y66 | Phosphorylation | Uniprot | |
| K92 | Acetylation | Uniprot | |
| K92 | Ubiquitination | Uniprot | |
| S101 | Phosphorylation | Uniprot | |
| K104 | Acetylation | Uniprot | |
| S119 | Phosphorylation | Uniprot | |
| S121 | Phosphorylation | Uniprot | |
| S125 | Phosphorylation | Uniprot | |
| K135 | Ubiquitination | Uniprot | |
| S136 | Phosphorylation | Uniprot | |
| T137 | Phosphorylation | Uniprot | |
| K152 | Acetylation | Uniprot | |
| K159 | Acetylation | Uniprot | |
| K160 | Acetylation | Uniprot | |
| T166 | Phosphorylation | Uniprot | |
| Y169 | Phosphorylation | Uniprot | |
| S278 | Phosphorylation | Uniprot | |
| S283 | Phosphorylation | Uniprot | |
| S284 | Phosphorylation | Uniprot | |
| Y285 | Phosphorylation | Uniprot | |
| T286 | Phosphorylation | Uniprot | |
| K289 | Acetylation | Uniprot | |
| K349 | Ubiquitination | Uniprot | |
| K359 | Acetylation | Uniprot | |
| K393 | Acetylation | Uniprot |
研究背景
Able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species. Has a preference for 3-trans substrates (By similarity).
Mitochondrion.
Peroxisome matrix.
Abundant in heart, skeletal muscle and liver. Expressed in CD34(+) T-cells and CD34(+) bone marrow cells.
In the C-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
研究领域
· Cellular Processes > Transport and catabolism > Peroxisome. (View pathway)
· Metabolism > Lipid metabolism > Fatty acid degradation.
限制条款
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