PABPC5 Antibody - #DF4303

(4)  
产品: PABPC5 抗体
货号: DF4303
描述: Rabbit polyclonal antibody to PABPC5
应用: WB IHC IF/ICC
反应: Human, Rat
预测: Horse, Rabbit
分子量: 43 KD; 43kD(Calculated).
蛋白号: Q96DU9
RRID: AB_2836654

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 50ul RMB¥ 1250 现货
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产品描述

来源:
Rabbit
应用:
WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Rat
预测:
Horse(86%), Rabbit(86%)
克隆:
Polyclonal
特异性:
PABPC5 Antibody detects endogenous levels of total PABPC5.
RRID:
AB_2836654
引用格式: Affinity Biosciences Cat# DF4303, RRID:AB_2836654.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

PABP5; Poly(A) binding protein 5; Poly(A) binding protein cytoplasmic 5; Polyadenylate binding protein 5;

抗原和靶标

免疫原:
Uniprot:

Q96DU9(PABP5_HUMAN) >>Visit HPA database.

基因/基因ID:
PABPC5(140886)
表达:
Q96DU9 PABP5_HUMAN:

Expressed in fetal brain and in a range of adult tissues.

序列:
MGSGEPNPAGKKKKYLKAALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEWALNTMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNLDKSIDNRALFYLFSAFGNILSCKVVCDDNGSKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVGRFKFPEERAAEVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKGFGFVRYETHEAAQKAVLDLHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPPGVPIYIKNLDETINDEKLKEEFSSFGSISRAKVMMEVGQGKGFGVVCFSSFEEATKAVDEMNGRIVGSKPLHVTLGQARRRC

种属预测

种属预测:

score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。

Species
Results
Score
Rabbit
86
Horse
86
Bovine
79
Sheep
79
Dog
79
Pig
71
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - Q96DU9 作为底物

Site PTM Type Enzyme
Y15 Phosphorylation
Y35 Phosphorylation
K102 Ubiquitination
S103 Phosphorylation
K111 Acetylation
K111 Ubiquitination
K115 Ubiquitination
Y147 Phosphorylation
Y149 Phosphorylation
S154 Phosphorylation
T199 Phosphorylation
S235 Phosphorylation
S238 Phosphorylation
Y270 Phosphorylation

研究背景

功能:

Binds the poly(A) tail of mRNA. May be involved in cytoplasmic regulatory processes of mRNA metabolism. Can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo (By similarity).

细胞定位:

Cytoplasm.

Mitochondrion matrix.
Note: Co-fractionates with mtDNA and co-immunoprecipitates with the mitochondrial poly(A) polymerase.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Expressed in fetal brain and in a range of adult tissues.

研究领域

· Genetic Information Processing > Translation > RNA transport.

· Genetic Information Processing > Translation > mRNA surveillance pathway.

· Genetic Information Processing > Folding, sorting and degradation > RNA degradation.

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