TAF3 Antibody - #DF4575

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产品: TAF3 抗体
货号: DF4575
描述: Rabbit polyclonal antibody to TAF3
应用: WB IHC
反应: Human, Mouse, Rat
预测: Zebrafish, Bovine, Rabbit, Dog, Chicken, Xenopus
分子量: 100 KD; 104kD(Calculated).
蛋白号: Q5VWG9
RRID: AB_2836939

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

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MS Report
HPLC Report
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说明书
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实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
IHC 1:50-1:200, WB 1:500-1:1000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse,Rat
预测:
Zebrafish(88%), Bovine(100%), Rabbit(100%), Dog(100%), Chicken(100%), Xenopus(100%)
克隆:
Polyclonal
特异性:
TAF3 Antibody detects endogenous levels of total TAF3.
RRID:
AB_2836939
引用格式: Affinity Biosciences Cat# DF4575, RRID:AB_2836939.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

140 kDa TATA box-binding protein-associated factor; Bip2 protein; RNA polymerase II transcription factor TAFII140; TAF(II)140; TAF140; TAF3; TAF3 RNA polymerase II TATA box binding protein (TBP)-associated factor; TAF3_HUMAN; TAFII-140; TAFII140; TAFII155 protein; TATA box binding protein associated factor 3; TBP-associated factor 3; Transcription initiation factor TFIID 140 kDa subunit; Transcription initiation factor TFIID subunit 3;

抗原和靶标

免疫原:
Uniprot:

Q5VWG9(TAF3_HUMAN) >>Visit HPA database.

基因/基因ID:
TAF3(83860)
序列:
MCESYSRSLLRVSVAQICQALGWDSVQLSACHLLTDVLQRYLQQLGRGCHRYSELYGRTDPILDDVGEAFQLMGVSLHELEDYIHNIEPVTFPHQIPSFPVSKNNVLQFPQPGSKDAEERKEYIPDYLPPIVSSQEEEEEEQVPTDGGTSAEAMQVPLEEDDELEEEEIINDENFLGKRPLDSPEAEELPAMKRPRLLSTKGDTLDVVLLEAREPLSSINTQKIPPMLSPVHVQDSTDLAPPSPEPPMLAPVAKSQMPTAKPLETKSFTPKTKTKTSSPGQKTKSPKTAQSPAMVGSPIRSPKTVSKEKKSPGRSKSPKSPKSPKVTTHIPQTPVRPETPNRTPSATLSEKISKETIQVKQIQTPPDAGKLNSENQPKKAVVADKTIEASIDAVIARACAEREPDPFEFSSGSESEGDIFTSPKRISGPECTTPKASTSANNFTKSGSTPLPLSGGTSSSDNSWTMDASIDEVVRKAKLGTPSNMPPNFPYISSPSVSPPTPEPLHKVYEEKTKLPSSVEVKKKLKKELKTKMKKKEKQRDREREKDKNKDKSKEKDKVKEKEKDKETGRETKYPWKEFLKEEEADPYKFKIKEFEDVDPKVKLKDGLVRKEKEKHKDKKKDREKGKKDKDKREKEKVKDKGREDKMKAPAPPLVLPPKELALPLFSPATASRVPAMLPSLLPVLPEKLFEEKEKVKEKEKKKDKKEKKKKKEKEKEKKEKEREKEKREREKREKEKEKHKHEKIKVEPVALAPSPVIPRLTLRVGAGQDKIVISKVVPAPEAKPAPSQNRPKTPPPAPAPAPGPMLVSPAPVPLPLLAQAAAGPALLPSPGPAASGASAKAPVRSVVTETVSTYVIRDEWGNQIWICPGCNKPDDGSPMIGCDDCDDWYHWPCVGIMTAPPEEMQWFCPKCANKKKDKKHKKRKHRAH

种属预测

种属预测:

score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。

Species
Results
Score
Bovine
100
Dog
100
Xenopus
100
Chicken
100
Rabbit
100
Zebrafish
88
Pig
0
Horse
0
Sheep
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - Q5VWG9 作为底物

Site PTM Type Enzyme
Y52 Phosphorylation
Y56 Phosphorylation
S114 Phosphorylation
S183 Phosphorylation
S199 Phosphorylation
T200 Phosphorylation
T204 Phosphorylation
S229 Phosphorylation
S236 Phosphorylation
T237 Phosphorylation
S243 Phosphorylation
K261 Acetylation
T265 Phosphorylation
K266 Acetylation
S267 Phosphorylation
T269 Phosphorylation
T288 Phosphorylation
S291 Phosphorylation
S297 Phosphorylation
S301 Phosphorylation
S315 Phosphorylation
S317 Phosphorylation
S320 Phosphorylation
S323 Phosphorylation
T333 Phosphorylation
T339 Phosphorylation
T343 Phosphorylation
T347 Phosphorylation
S349 Phosphorylation
T364 Phosphorylation
K370 Ubiquitination
S373 Phosphorylation
S410 Phosphorylation
S411 Phosphorylation
S413 Phosphorylation
S415 Phosphorylation
S427 Phosphorylation
T432 Phosphorylation
T433 Phosphorylation
S483 Phosphorylation
Y491 Phosphorylation
S493 Phosphorylation
S494 Phosphorylation
S496 Phosphorylation
S498 Phosphorylation
T501 Phosphorylation
S517 Phosphorylation
S518 Phosphorylation
T568 Phosphorylation
T572 Phosphorylation
K601 Acetylation
K621 Acetylation
K625 Acetylation
K628 Acetylation
S667 Phosphorylation
K746 Sumoylation
S755 Phosphorylation
T762 Phosphorylation
K776 Acetylation
T794 Phosphorylation
S809 Phosphorylation

研究背景

功能:

Transcription factor TFIID is one of the general factors required for accurate and regulated initiation by RNA polymerase II. TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. Required in complex with TBPL2 for the differentiation of myoblasts into myocytes. The complex replaces TFIID at specific promoters at an early stage in the differentiation process.

细胞定位:

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
亚基结构:

Belongs to the TFIID complex which is composed of TATA binding protein (TBP) and a number of TBP-associated factors (TAFs). Interacts with TAF10 via the histone fold. Interacts with TAF13, TBP, SAP130 and GCN5L2. Interacts with TBPL2.

蛋白家族:

The PHD-type zinc finger mediates binding to histone H3 methyllysine at position 4 (H3K4me3).

Belongs to the TAF3 family.

研究领域

· Genetic Information Processing > Transcription > Basal transcription factors.

· Human Diseases > Infectious diseases: Viral > Herpes simplex infection.

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