产品: TMPRSS4 抗体
货号: DF12037
描述: Rabbit polyclonal antibody to TMPRSS4
应用: WB IHC IF/ICC
反应: Human, Mouse, Rat
预测: Pig, Bovine, Horse, Sheep, Rabbit, Dog
分子量: 55 kDa; 48kD(Calculated).
蛋白号: Q9NRS4
RRID: AB_2844842

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产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse,Rat
预测:
Pig(90%), Bovine(90%), Horse(89%), Sheep(90%), Rabbit(90%), Dog(90%)
克隆:
Polyclonal
特异性:
TMPRSS4 Antibody detects endogenous levels of total TMPRSS4.
RRID:
AB_2844842
引用格式: Affinity Biosciences Cat# DF12037, RRID:AB_2844842.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

UNQ776/PRO1570; CAPH2; Channel-activating protease 2; Membrane type serine protease 2; Membrane-type serine protease 2; MT SP2; MT-SP2; TMPRSS 4; TMPRSS3; TMPRSS4; TMPS4_HUMAN; Transmembrane protease serine 4; Transmembrane protease, serine 4; Transmembrane serine protease 3;

抗原和靶标

免疫原:
Uniprot:
基因/基因ID:
表达:
Q9NRS4 TMPS4_HUMAN:

High levels in pancreatic, gastric, colorectal and ampullary cancer. Very weak expression in normal gastrointestinal and urogenital tract.

序列:
MLQDPDSDQPLNSLDVKPLRKPRIPMETFRKVGIPIIIALLSLASIIIVVVLIKVILDKYYFLCGQPLHFIPRKQLCDGELDCPLGEDEEHCVKSFPEGPAVAVRLSKDRSTLQVLDSATGNWFSACFDNFTEALAETACRQMGYSSKPTFRAVEIGPDQDLDVVEITENSQELRMRNSSGPCLSGSLVSLHCLACGKSLKTPRVVGVEEASVDSWPWQVSIQYDKQHVCGGSILDPHWVLTAAHCFRKHTDVFNWKVRAGSDKLGSFPSLAVAKIIIIEFNPMYPKDNDIALMKLQFPLTFSGTVRPICLPFFDEELTPATPLWIIGWGFTKQNGGKMSDILLQASVQVIDSTRCNADDAYQGEVTEKMMCAGIPEGGVDTCQGDSGGPLMYQSDQWHVVGIVSWGYGCGGPSTPGVYTKVSAYLNWIYNVWKAEL

种属预测

种属预测:

score>80的预测可信度较高,可尝试用于WB检测。*预测模型主要基于免疫原序列比对,结果仅作参考,不作为质保凭据。

Species
Results
Score
Pig
90
Bovine
90
Sheep
90
Dog
90
Rabbit
90
Horse
89
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - Q9NRS4 作为底物

Site PTM Type Enzyme
T28 Phosphorylation

研究背景

功能:

Probable protease. Seems to be capable of activating ENaC (By similarity).

细胞定位:

Membrane>Single-pass type II membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

High levels in pancreatic, gastric, colorectal and ampullary cancer. Very weak expression in normal gastrointestinal and urogenital tract.

蛋白家族:

Belongs to the peptidase S1 family.

研究领域

· Human Diseases > Infectious diseases: Viral > Influenza A.

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