| 产品: | TXNDC5 抗体 |
| 货号: | DF12787 |
| 描述: | Rabbit polyclonal antibody to TXNDC5 |
| 应用: | WB IF/ICC |
| 反应: | Human, Mouse, Rat |
| 预测: | Pig |
| 分子量: | 48 kDa; 48kD(Calculated). |
| 蛋白号: | Q8NBS9 |
| RRID: | AB_2845748 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF12787, RRID:AB_2845748.
展开/折叠
EndoPDI; Endoplasmic reticulum protein ERp46; Endoplasmic reticulum resident protein 46; Endothelial protein disulphide isomerase; ER protein 46; ERp46; Hcc 2; MGC3178; PDIA15; Protein disulfide isomerase family A member 15; STRF8; Thioredoxin domain containing 5 (endoplasmic reticulum); Thioredoxin domain containing 5; Thioredoxin domain containing protein 5; Thioredoxin domain-containing protein 5; Thioredoxin like protein p46; Thioredoxin related protein; Thioredoxin-like protein p46; TLP46; TXND5_HUMAN; TXNDC 5; Txndc5;
抗原和靶标
- Q8NBS9 TXND5_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MPARPGRLLPLLARPAALTALLLLLLGHGGGGRWGARAQEAAAAAADGPPAADGEDGQDPHSKHLYTADMFTHGIQSAAHFVMFFAPWCGHCQRLQPTWNDLGDKYNSMEDAKVYVAKVDCTAHSDVCSAQGVRGYPTLKLFKPGQEAVKYQGPRDFQTLENWMLQTLNEEPVTPEPEVEPPSAPELKQGLYELSASNFELHVAQGDHFIKFFAPWCGHCKALAPTWEQLALGLEHSETVKIGKVDCTQHYELCSGNQVRGYPTLLWFRDGKKVDQYKGKRDLESLREYVESQLQRTETGATETVTPSEAPVLAAEPEADKGTVLALTENNFDDTIAEGITFIKFYAPWCGHCKTLAPTWEELSKKEFPGLAGVKIAEVDCTAERNICSKYSVRGYPTLLLFRGGKKVSEHSGGRDLDSLHRFVLSQAKDEL
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q8NBS9 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T72 | O-Glycosylation | Uniprot | |
| S108 | Phosphorylation | Uniprot | |
| K113 | Ubiquitination | Uniprot | |
| Y115 | Phosphorylation | Uniprot | |
| K118 | Ubiquitination | Uniprot | |
| T122 | Phosphorylation | Uniprot | |
| S125 | Phosphorylation | Uniprot | |
| S129 | Phosphorylation | Uniprot | |
| R134 | Methylation | Uniprot | |
| K143 | Ubiquitination | Uniprot | |
| K150 | Ubiquitination | Uniprot | |
| K221 | Methylation | Uniprot | |
| K241 | Ubiquitination | Uniprot | |
| K244 | Ubiquitination | Uniprot | |
| T248 | Phosphorylation | Uniprot | |
| Y251 | Phosphorylation | Uniprot | |
| Y289 | Phosphorylation | Uniprot | |
| K344 | Ubiquitination | Uniprot | |
| K366 | Ubiquitination | Uniprot | |
| K390 | Acetylation | Uniprot | |
| S419 | Phosphorylation | Uniprot | |
| S426 | Phosphorylation | Uniprot | |
| K429 | Ubiquitination | Uniprot |
研究背景
Possesses thioredoxin activity. Has been shown to reduce insulin disulfide bonds. Also complements protein disulfide-isomerase deficiency in yeast (By similarity).
Endoplasmic reticulum lumen.
Belongs to the protein disulfide isomerase family.
研究领域
· Genetic Information Processing > Folding, sorting and degradation > Protein processing in endoplasmic reticulum. (View pathway)
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