产品: RASA3 抗体
货号: DF4386
描述: Rabbit polyclonal antibody to RASA3
应用: WB IF/ICC
反应: Human, Mouse, Rat
预测: Pig, Bovine, Dog, Chicken
分子量: 96 KD; 96kD(Calculated).
蛋白号: Q14644
RRID: AB_2836741

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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产品描述

来源:
Rabbit
应用:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse,Rat
预测:
Pig(88%), Bovine(88%), Dog(88%), Chicken(88%)
克隆:
Polyclonal
特异性:
RASA3 Antibody detects endogenous levels of total RASA3.
RRID:
AB_2836741
引用格式: Affinity Biosciences Cat# DF4386, RRID:AB_2836741.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

GAP III; GAP1(IP4BP); GAP1IP4BP; GAPIII; GTPase activating protein 1 family; GTPase activating protein III; Inositol 1 3 4 5 tetrakisphosphate binding protein; Inositol 1345 tetrakisphosphate binding protein; Ins P4 binding protein; Ins P4-binding protein; Ins(1 3 4 5)P4 binding protein; Ins(1345)P4 binding protein; MGC46517; MGC47588; Ras GTPase activating protein 3; Ras GTPase-activating protein 3; RAS p21 protein activator 3; RASA 3; RASA3; RASA3_HUMAN;

抗原和靶标

免疫原:
Uniprot:
基因/基因ID:
序列:
MAVEDEGLRVFQSVKIKIGEAKNLPSYPGPSKMRDCYCTVNLDQEEVFRTKIVEKSLCPFYGEDFYCEIPRSFRHLSFYIFDRDVFRRDSIIGKVAIQKEDLQKYHNRDTWFQLQHVDADSEVQGKVHLELRLSEVITDTGVVCHKLATRIVECQGLPIVNGQCDPYATVTLAGPFRSEAKKTKVKRKTNNPQFDEVFYFEVTRPCSYSKKSHFDFEEEDVDKLEIRVDLWNASNLKFGDEFLGELRIPLKVLRQSSSYEAWYFLQPRDNGSKSLKPDDLGSLRLNVVYTEDHVFSSDYYSPLRDLLLKSADVEPVSASAAHILGEVCREKQEAAVPLVRLFLHYGRVVPFISAIASAEVKRTQDPNTIFRGNSLASKCIDETMKLAGMHYLHVTLKPAIEEICQSHKPCEIDPVKLKDGENLENNMENLRQYVDRVFHAITESGVSCPTVMCDIFFSLREAAAKRFQDDPDVRYTAVSSFIFLRFFAPAILSPNLFQLTPHHTDPQTSRTLTLISKTVQTLGSLSKSKSASFKESYMATFYEFFNEQKYADAVKNFLDLISSSGRRDPKSVEQPIVLKEGFMIKRAQGRKRFGMKNFKKRWFRLTNHEFTYHKSKGDQPLYSIPIENILAVEKLEEESFKMKNMFQVIQPERALYIQANNCVEAKDWIDILTKVSQCNQKRLTVYHPSAYLSGHWLCCRAPSDSAPGCSPCTGGLPANIQLDIDGDRETERIYSLFNLYMSKLEKMQEACGSKSVYDGPEQEEYSTFVIDDPQETYKTLKQVIAGVGALEQEHAQYKRDKFKKTKYGSQEHPIGDKSFQNYIRQQSETSTHSI

种属预测

种属预测:

score>80的预测可信度较高,可尝试用于WB检测。*预测模型主要基于免疫原序列比对,结果仅作参考,不作为质保凭据。

Species
Results
Score
Pig
88
Bovine
88
Dog
88
Chicken
88
Horse
0
Sheep
0
Xenopus
0
Zebrafish
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - Q14644 作为底物

Site PTM Type Enzyme
A2 Acetylation
S13 Phosphorylation
K15 Ubiquitination
K32 Ubiquitination
K55 Ubiquitination
Y61 Phosphorylation
Y66 Phosphorylation
S77 Phosphorylation
Y79 Phosphorylation
S90 Phosphorylation
K99 Ubiquitination
K104 Ubiquitination
T110 Phosphorylation
K146 Ubiquitination
Y199 Phosphorylation
T203 Phosphorylation
S207 Phosphorylation
Y208 Phosphorylation
K223 Acetylation
K237 Ubiquitination
K251 Ubiquitination
S257 Phosphorylation
K273 Ubiquitination
K276 Ubiquitination
S282 Phosphorylation
K309 Ubiquitination
Y345 Phosphorylation
K378 Ubiquitination
T450 Phosphorylation
T511 Phosphorylation
T518 Phosphorylation
T521 Phosphorylation
S524 Phosphorylation
S526 Phosphorylation
K527 Acetylation
K527 Ubiquitination
K529 Acetylation
S532 Phosphorylation
K555 Ubiquitination
S562 Phosphorylation
S563 Phosphorylation
S564 Phosphorylation
K570 Ubiquitination
K579 Ubiquitination
K596 Acetylation
K599 Acetylation
K616 Ubiquitination
K634 Ubiquitination
K641 Ubiquitination
K643 Ubiquitination
K674 Ubiquitination
S703 Phosphorylation
K746 Ubiquitination
Y757 Phosphorylation
T776 Phosphorylation
Y777 Phosphorylation
K778 Ubiquitination
K781 Ubiquitination
Y797 Phosphorylation
T805 Phosphorylation
K806 Ubiquitination
Y807 Phosphorylation
S809 Phosphorylation
K817 Ubiquitination
S818 Phosphorylation
Y822 Phosphorylation
S827 Phosphorylation
T829 Phosphorylation
S830 Phosphorylation
T831 Phosphorylation
S833 Phosphorylation

研究背景

功能:

Inhibitory regulator of the Ras-cyclic AMP pathway. Binds inositol tetrakisphosphate (IP4) with high affinity. Might be a specific IP4 receptor.

细胞定位:

Cell membrane.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location

研究领域

· Environmental Information Processing > Signal transduction > Ras signaling pathway.   (View pathway)

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