产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# AF0606, RRID:AB_2834280.
展开/折叠
COA 1; colorectal tumor associated antigen 1; Colorectal tumor associated antigen COA 1; PP2243; SOC; SOCI; Socius; UBX domain containing 5; UBX domain containing protein 11; UBX domain containing protein 5; UBXD 5; UBXN11;
抗原和靶标
- Q5T124 UBX11_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSSPLASLSKTRKVPLPSEPMNPGRRGIRIYGDEDEVDMLSDGCGSEEKISVPSCYGGIGAPVSRQVPASHDSELMAFMTRKLWDLEQQVKAQTDEILSKDQKIAALEDLVQTLRPHPAEATLQRQEELETMCVQLQRQVREMERFLSDYGLQWVGEPMDQEDSESKTVSEHGERDWMTAKKFWKPGDSLAPPEVDFDRLLASLQDLSELVVEGDTQVTPVPGGARLRTLEPIPLKLYRNGIMMFDGPFQPFYDPSTQRCLRDILDGFFPSELQRLYPNGVPFKVSDLRNQVYLEDGLDPFPGEGRVVGRQLMHKALDRVEEHPGSRMTAEKFLNRLPKFVIRQGEVIDIRGPIRDTLQNCCPLPARIQEIVVETPTLAAERERSQESPNTPAPPLSMLRIKSENGEQAFLLMMQPDNTIGDVRALLAQARVMDASAFEIFSTFPPTLYQDDTLTLQAAGLVPKAALLLRARRAPKSSLKFSPGPCPGPGPGPSPGPGPGPSPGPGPGPSPCPGPSPSPQ
种属预测
score>80的预测可信度较高,可尝试用于WB检测。*预测模型主要基于免疫原序列比对,结果仅作参考,不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q5T124 作为底物
Site | PTM Type | Enzyme | Source |
---|---|---|---|
S3 | Phosphorylation | Uniprot | |
S9 | Phosphorylation | Uniprot | |
K13 | Ubiquitination | Uniprot | |
S70 | Phosphorylation | Uniprot | |
S73 | Phosphorylation | Uniprot | |
T80 | Phosphorylation | Uniprot | |
K100 | Ubiquitination | Uniprot | |
S208 | Phosphorylation | Uniprot | |
K236 | Ubiquitination | Uniprot | |
K284 | Ubiquitination | Uniprot | |
K402 | Ubiquitination | Uniprot |
研究背景
May be involved in the reorganization of actin cytoskeleton mediated by RND1, RND2 AND RND3. Promotes RHOA activation mediated by GNA12 and GNA13 (By similarity).
Cytoplasm>Cytoskeleton.
Interacts with GNA12, GNA13, RND1, RND2 AND RND3.
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