| 产品: | SFXN4 抗体 |
| 货号: | AF0580 |
| 描述: | Rabbit polyclonal antibody to SFXN4 |
| 应用: | WB IF/ICC |
| 反应: | Human |
| 分子量: | 37kDa; 38kD(Calculated). |
| 蛋白号: | Q6P4A7 |
| RRID: | AB_2834289 |
产品描述
来源:
Rabbit
应用:
WB 1:500-1:2000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
反应:
Human
克隆:
Polyclonal
特异性:
SFXN4 Antibody detects endogenous levels of total SFXN4.
RRID:
AB_2834289
引用格式: Affinity Biosciences Cat# AF0580, RRID:AB_2834289.
引用格式: Affinity Biosciences Cat# AF0580, RRID:AB_2834289.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:
展开/折叠
BCRM1; Breast cancer resistance marker 1; SFXN 4; Sideroflexin 4;
抗原和靶标
免疫原:
Uniprot:
基因/基因ID:
描述:
Sfxn4 Potential iron transporter. Belongs to the sideroflexin family. 3 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
序列:
- Q6P4A7 SFXN4_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSLEQEEETQPGRLLGRRDAVPAFIEPNVRFWITERQSFIRRFLQWTELLDPTNVFISVESIENSRQLLCTNEDVSSPASADQRIQEAWKRSLATVHPDSSNLIPKLFRPAAFLPFMAPTVFLSMTPLKGIKSVILPQVFLCAYMAAFNSINGNRSYTCKPLERSLLMAGAVASSTFLGVIPQFVQMKYGLTGPWIKRLLPVIFLVQASGMNVYMSRSLESIKGIAVMDKEGNVLGHSRIAGTKAVRETLASRIVLFGTSALIPEVFTYFFKRTQYFRKNPGSLWILKLSCTVLAMGLMVPFSFSIFPQIGQIQYCSLEEKIQSPTEETEIFYHRGV
翻译修饰 - Q6P4A7 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S2 | Acetylation | Uniprot | |
| S2 | Phosphorylation | Uniprot | |
| K90 | Ubiquitination | Uniprot | |
| K106 | Ubiquitination | Uniprot | |
| C159 | S-Nitrosylation | Uniprot | |
| K160 | Ubiquitination | Uniprot | |
| K197 | Acetylation | Uniprot | |
| K197 | Ubiquitination | Uniprot | |
| S209 | Phosphorylation | Uniprot | |
| K223 | Ubiquitination | Uniprot | |
| K230 | Ubiquitination | Uniprot | |
| S324 | Phosphorylation | Uniprot |
研究背景
功能:
Mitochondrial amino-acid transporter (By similarity). Does not act as a serine transporter: not able to mediate transport of serine into mitochondria.
细胞定位:
Mitochondrion inner membrane>Multi-pass membrane protein.
蛋白家族:
Belongs to the sideroflexin family.
限制条款
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