| 产品: | AL2S7 抗体 |
| 货号: | AF0509 |
| 描述: | Rabbit polyclonal antibody to AL2S7 |
| 应用: | WB IF/ICC |
| 反应: | Human, Mouse |
| 预测: | Pig, Sheep, Rabbit, Dog |
| 分子量: | 46kDa; 49kD(Calculated). |
| 蛋白号: | Q96Q40 |
| RRID: | AB_2834303 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# AF0509, RRID:AB_2834303.
展开/折叠
A2S7; AL2S7; ALS2CR7; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 7 protein; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7; CDK15; CDK15_HUMAN; Cell division protein kinase 15; Cyclin-dependent kinase 15; EC 2.7.11.22; PFTAIRE protein kinase 2; PFTAIRE2; PFTK2; Serine/threonine protein kinase ALS2CR7; Serine/threonine protein kinase PFTAIRE 2; Serine/threonine-protein kinase ALS2CR7; Serine/threonine-protein kinase PFTAIRE-2;
抗原和靶标
- Q96Q40 CDK15_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGQELCAKTVQPGCSCYHCSEGGEAHSCRRSQPETTEAAFKLTDLKEASCSMTSFHPRGLQAARAQKFKSKRPRSNSDCFQEEDLRQGFQWRKSLPFGAASSYLNLEKLGEGSYATVYKGISRINGQLVALKVISMNAEEGVPFTAIREASLLKGLKHANIVLLHDIIHTKETLTFVFEYMHTDLAQYMSQHPGGLHPHNVRLFMFQLLRGLAYIHHQHVLHRDLKPQNLLISHLGELKLADFGLARAKSIPSQTYSSEVVTLWYRPPDALLGATEYSSELDIWGAGCIFIEMFQGQPLFPGVSNILEQLEKIWEVLGVPTEDTWPGVSKLPNYNPEWFPLPTPRSLHVVWNRLGRVPEAEDLASQMLKGFPRDRVSAQEALVHDYFSALPSQLYQLPDEESLFTVSGVRLKPEMCDLLASYQKGHHPAQFSKCW
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q96Q40 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K108 | Ubiquitination | Uniprot | |
| Y114 | Phosphorylation | Uniprot | |
| Y118 | Phosphorylation | Uniprot | |
| T170 | Phosphorylation | Uniprot | |
| K239 | Ubiquitination | Uniprot | |
| T343 | Phosphorylation | Uniprot |
研究背景
Serine/threonine-protein kinase that acts like an antiapoptotic protein that counters TRAIL/TNFSF10-induced apoptosis by inducing phosphorylation of BIRC5 at 'Thr-34'.
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
限制条款
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