| 产品: | UBE2G1 抗体 |
| 货号: | DF10001 |
| 描述: | Rabbit polyclonal antibody to UBE2G1 |
| 应用: | WB |
| 反应: | Human, Mouse, Rat, Monkey |
| 预测: | Pig, Bovine, Horse, Sheep, Dog, Chicken, Xenopus |
| 分子量: | 20 kDa; 20kD(Calculated). |
| 蛋白号: | P62253 |
| RRID: | AB_2840581 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF10001, RRID:AB_2840581.
展开/折叠
E217K; UB2G1_HUMAN; UBC 7; UBC7; UBC7 homolog yeast; UBE 2G; UBE2G; Ube2g1; Ubiquitin carrier protein G1; Ubiquitin conjugating enzyme E2 G1; Ubiquitin conjugating enzyme E2G 1 (homologous to C. elegans UBC7); Ubiquitin conjugating enzyme E2G 1 (UBC7 homolog C. elegans); Ubiquitin conjugating enzyme E2G 1 (UBC7 homolog yeast); Ubiquitin conjugating enzyme E2G 1; Ubiquitin protein ligase G1; Ubiquitin-conjugating enzyme E2 G1; Ubiquitin-protein ligase G1;
抗原和靶标
- P62253 UB2G1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MTELQSALLLRRQLAELNKNPVEGFSAGLIDDNDLYRWEVLIIGPPDTLYEGGVFKAHLTFPKDYPLRPPKMKFITEIWHPNVDKNGDVCISILHEPGEDKYGYEKPEERWLPIHTVETIMISVISMLADPNGDSPANVDAAKEWREDRNGEFKRKVARCVRKSQETAFE
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P62253 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| M1 | Acetylation | Uniprot | |
| T2 | Acetylation | Uniprot | |
| T2 | Phosphorylation | Uniprot | |
| S6 | Phosphorylation | Uniprot | |
| K19 | Ubiquitination | Uniprot | |
| K63 | Ubiquitination | Uniprot | |
| Y65 | Phosphorylation | Uniprot | |
| K73 | Ubiquitination | Uniprot | |
| T76 | Phosphorylation | Uniprot | |
| K101 | Ubiquitination | Uniprot | |
| Y102 | Phosphorylation | Uniprot | |
| Y104 | Phosphorylation | Uniprot | |
| K106 | Ubiquitination | Uniprot | |
| K163 | Ubiquitination | Uniprot |
研究背景
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-, as well as 'Lys-63'-linked polyubiquitination. May be involved in degradation of muscle-specific proteins. Mediates polyubiquitination of CYP3A4.
Autoubiquitinated in vitro.
Widely expressed, mainly in skeletal muscle.
Belongs to the ubiquitin-conjugating enzyme family.
研究领域
· Genetic Information Processing > Folding, sorting and degradation > Ubiquitin mediated proteolysis. (View pathway)
· Genetic Information Processing > Folding, sorting and degradation > Protein processing in endoplasmic reticulum. (View pathway)
· Human Diseases > Neurodegenerative diseases > Parkinson's disease.
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