RBAK Antibody - #AF0422

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产品: RBAK 抗体
货号: AF0422
描述: Rabbit polyclonal antibody to RBAK
应用: WB IF/ICC
反应: Human, Mouse, Rat
预测: Pig, Bovine, Horse, Sheep
分子量: 85kDa; 83kD(Calculated).
蛋白号: Q9NYW8
RRID: AB_2834340

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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相关下载
MS Report
HPLC Report
MSDS
说明书
COA
实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse,Rat
预测:
Pig(80%), Bovine(82%), Horse(91%), Sheep(82%)
克隆:
Polyclonal
特异性:
RBAK Antibody detects endogenous levels of total RBAK.
RRID:
AB_2834340
引用格式: Affinity Biosciences Cat# AF0422, RRID:AB_2834340.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

hRBaK; Hypothetical protein RBAK; RB associated KRAB zinc finger; RB-associated KRAB repressor; RB-associated KRAB zinc finger protein; RBAK; RBAK_HUMAN; Zinc finger protein 769; ZNF 769; ZNF769;

抗原和靶标

免疫原:
Uniprot:

Q9NYW8(RBAK_HUMAN) >>Visit HPA database.

基因/基因ID:
RBAK(57786)
表达:
Q9NYW8 RBAK_HUMAN:

Expressed in bone, brain, heart, kidney, liver, lung, pancreas and placenta.

描述:
RBAK May repress E2F-dependent transcription. May promote AR- dependent transcription. Belongs to the krueppel C2H2-type zinc-finger protein family. Interacts with AR and RB1. May also interact with other nuclear hormone receptors such as NR3C1/GR.
序列:
MNTLQGPVSFKDVAVDFTQEEWQQLDPDEKITYRDVMLENYSHLVSVGYDTTKPNVIIKLEQGEEPWIMGGEFPCQHSPEAWRVDDLIERIQENEDKHSRQAACINSKTLTEEKENTFSQIYMETSLVPSSIIAHNCVSCGKNLESISQLISSDGSYARTKPDECNECGKTYHGEKMCEFNQNGDTYSHNEENILQKISILEKPFEYNECMEALDNEAVFIAHKRAYIGEKPYEWNDSGPDFIQMSNFNAYQRSQMEMKPFECSECGKSFCKKSKFIIHQRAHTGEKPYECNVCGKSFSQKGTLTVHRRSHLEEKPYKCNECGKTFCQKLHLTQHLRTHSGEKPYECSECGKTFCQKTHLTLHQRNHSGERPYPCNECGKSFSRKSALSDHQRTHTGEKLYKCNECGKSYYRKSTLITHQRTHTGEKPYQCSECGKFFSRVSYLTIHYRSHLEEKPYECNECGKTFNLNSAFIRHRKVHTEEKSHECSECGKFSQLYLTDHHTAHLEEKPYECNECGKTFLVNSAFDGHQPLPKGEKSYECNVCGKLFNELSYYTEHYRSHSEEKPYGCSECGKTFSHNSSLFRHQRVHTGEKPYECYECGKFFSQKSYLTIHHRIHSGEKPYECSKCGKVFSRMSNLTVHYRSHSGEKPYECNECGKVFSQKSYLTVHYRTHSGEKPYECNECGKKFHHRSAFNSHQRIHRRGNMNVLDVENL

种属预测

种属预测:

score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。

Species
Results
Score
Horse
91
Bovine
82
Sheep
82
Pig
80
Dog
64
Xenopus
0
Zebrafish
0
Chicken
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - Q9NYW8 作为底物

Site PTM Type Enzyme
Y33 Phosphorylation
S78 Phosphorylation
K97 Sumoylation
K108 Sumoylation
K108 Ubiquitination
K161 Sumoylation
K259 Sumoylation
K275 Sumoylation
T284 Phosphorylation
K301 Sumoylation
K315 Sumoylation
K318 Sumoylation
K357 Sumoylation
S368 Phosphorylation
S386 Phosphorylation
S389 Phosphorylation
T394 Phosphorylation
T396 Phosphorylation
K399 Ubiquitination
T422 Phosphorylation
T424 Phosphorylation
K427 Sumoylation
K427 Ubiquitination
K455 Ubiquitination
K509 Ubiquitination
K534 Sumoylation
K537 Ubiquitination
S560 Phosphorylation
S562 Phosphorylation
K565 Sumoylation
Y567 Phosphorylation
S570 Phosphorylation
T590 Phosphorylation
Y595 Phosphorylation
Y598 Phosphorylation
Y609 Phosphorylation
S618 Phosphorylation
S633 Phosphorylation
T639 Phosphorylation
Y642 Phosphorylation
K649 Ubiquitination
K658 Sumoylation
K663 Sumoylation
K677 Ubiquitination

研究背景

功能:

May repress E2F-dependent transcription. May promote AR-dependent transcription.

细胞定位:

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Expressed in bone, brain, heart, kidney, liver, lung, pancreas and placenta.

亚基结构:

Interacts with AR and RB1. May also interact with other nuclear hormone receptors such as NR3C1/GR.

蛋白家族:

Belongs to the krueppel C2H2-type zinc-finger protein family.

限制条款

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