| 产品: | POLM 抗体 |
| 货号: | DF10080 |
| 描述: | Rabbit polyclonal antibody to POLM |
| 应用: | WB |
| 反应: | Human |
| 预测: | Pig, Zebrafish, Horse, Sheep, Rabbit |
| 分子量: | 55 kDa; 55kD(Calculated). |
| 蛋白号: | Q9NP87 |
| RRID: | AB_2840660 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF10080, RRID:AB_2840660.
展开/折叠
DNA-directed DNA polymerase mu; DNA-directed DNA/RNA polymerase mu; DPOLM_HUMAN; FLJ35482; Pol iota; Pol Mu; Polm; POLM protein; Polymerase (DNA directed) mu; Polymerase DNA directed mu; Tdt N; Tdt-N; TdtN; Terminal transferase;
抗原和靶标
- Q9NP87 DPOLM_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MLPKRRRARVGSPSGDAASSTPPSTRFPGVAIYLVEPRMGRSRRAFLTGLARSKGFRVLDACSSEATHVVMEETSAEEAVSWQERRMAAAPPGCTPPALLDISWLTESLGAGQPVPVECRHRLEVAGPRKGPLSPAWMPAYACQRPTPLTHHNTGLSEALEILAEAAGFEGSEGRLLTFCRAASVLKALPSPVTTLSQLQGLPHFGEHSSRVVQELLEHGVCEEVERVRRSERYQTMKLFTQIFGVGVKTADRWYREGLRTLDDLREQPQKLTQQQKAGLQHHQDLSTPVLRSDVDALQQVVEEAVGQALPGATVTLTGGFRRGKLQGHDVDFLITHPKEGQEAGLLPRVMCRLQDQGLILYHQHQHSCCESPTRLAQQSHMDAFERSFCIFRLPQPPGAAVGGSTRPCPSWKAVRVDLVVAPVSQFPFALLGWTGSKLFQRELRRFSRKEKGLWLNSHGLFDPEQKTFFQAASEEDIFRHLGLEYLPPEQRNA
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q9NP87 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S12 | Phosphorylation | Uniprot | |
| S14 | Phosphorylation | Uniprot | |
| S19 | Phosphorylation | Uniprot | |
| T21 | Phosphorylation | Uniprot | |
| T95 | Phosphorylation | Uniprot | |
| K187 | Ubiquitination | Uniprot | |
| K238 | Ubiquitination | Uniprot | |
| K249 | Ubiquitination | Uniprot | |
| K271 | Ubiquitination | Uniprot | |
| K277 | Ubiquitination | Uniprot | |
| K325 | Ubiquitination | Uniprot | |
| K339 | Ubiquitination | Uniprot | |
| S372 | Phosphorylation | P24941 (CDK2) | Uniprot |
| K452 | Ubiquitination | Uniprot | |
| K467 | Ubiquitination | Uniprot |
研究背景
Gap-filling polymerase involved in repair of DNA double-strand breaks by non-homologous end joining (NHEJ). Participates in immunoglobulin (Ig) light chain gene rearrangement in V(D)J recombination.
Nucleus.
Expressed in a number of tissues. Abundant in thymus.
Belongs to the DNA polymerase type-X family.
研究领域
· Genetic Information Processing > Replication and repair > Non-homologous end-joining.
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