产品: | COX7A2L 抗体 |
货号: | DF10094 |
描述: | Rabbit polyclonal antibody to COX7A2L |
应用: | WB |
反应: | Human, Mouse, Rat |
预测: | Pig, Bovine, Horse, Dog |
分子量: | 13 kDa; 13kD(Calculated). |
蛋白号: | O14548 |
RRID: | AB_2840674 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF10094, RRID:AB_2840674.
展开/折叠
COX7a related protein; COX7a-related protein; COX7A2L; COX7AR; COX7R_HUMAN; COX7RP; Cytochrome c oxidase subunit 7A-related protein; cytochrome c oxidase subunit 7A-related protein, mitochondrial; cytochrome c oxidase subunit VII-related protein; cytochrome c oxidase subunit VIIa polypeptide 2 like; Cytochrome c oxidase subunit VIIa related protein, mitochondrial; Cytochrome c oxidase subunit VIIa-related protein; EB1; Estrogen receptor binding CpG island; mitochondrial; SIG81;
抗原和靶标
- O14548 COX7R_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MYYKFSGFTQKLAGAWASEAYSPQGLKPVVSTEAPPIIFATPTKLTSDSTVYDYAGKNKVPELQKFFQKADGVPVYLKRGLPDQMLYRTTMALTVGGTIYCLIALYMASQPKNK
种属预测
score>80的预测可信度较高,可尝试用于WB检测。*预测模型主要基于免疫原序列比对,结果仅作参考,不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - O14548 作为底物
Site | PTM Type | Enzyme | Source |
---|---|---|---|
K4 | Acetylation | Uniprot | |
K11 | Ubiquitination | Uniprot | |
S47 | Phosphorylation | Uniprot | |
Y52 | Phosphorylation | Uniprot | |
K57 | Ubiquitination | Uniprot | |
K69 | Acetylation | Uniprot | |
K69 | Ubiquitination | Uniprot | |
Y87 | Phosphorylation | Uniprot |
研究背景
Involved in the regulation of oxidative phosphorylation and energy metabolism (By similarity). Necessary for the assembly of mitochondrial respiratory supercomplex (By similarity).
Mitochondrion inner membrane.
Interacts with the mitochondrial respiratory supercomplex.
Belongs to the cytochrome c oxidase VIIa family.
研究领域
· Human Diseases > Endocrine and metabolic diseases > Non-alcoholic fatty liver disease (NAFLD).
· Human Diseases > Neurodegenerative diseases > Alzheimer's disease.
· Human Diseases > Neurodegenerative diseases > Parkinson's disease.
· Human Diseases > Neurodegenerative diseases > Huntington's disease.
· Metabolism > Energy metabolism > Oxidative phosphorylation.
· Organismal Systems > Circulatory system > Cardiac muscle contraction. (View pathway)
限制条款
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