KRT81/86 Antibody - #DF10117

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产品: KRT81/86 抗体
货号: DF10117
描述: Rabbit polyclonal antibody to KRT81/86
应用: WB IHC
反应: Human, Mouse
分子量: 54 kDa; 54kD,55kD(Calculated).
蛋白号: O43790 | Q14533
RRID: AB_2840697

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   规格 价格 库存
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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MS Report
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WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:1000-3000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse
克隆:
Polyclonal
特异性:
KRT81/86 Antibody detects endogenous levels of total KRT81/86.
RRID:
AB_2840697
引用格式: Affinity Biosciences Cat# DF10117, RRID:AB_2840697.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

Hair keratin K2.11; Hb6; K86; Keratin; Keratin-86; KRT86; KRT86_HUMAN; KRTHB6; MNX; type II cuticular Hb6; Type II hair keratin Hb6; Type-II keratin Kb26; 1; basic; ghHb 1; ghHb1; ghHkb 1; ghHKb1; hair; Hair keratin K2.9; Hard keratin type II 1; HB 1; HB1; hHAKB2 1; K2.9; K81; Keratin 81; Keratin; Keratin hair basic 1; Keratin type II cuticular Hb1; Keratin-81; Keratin81; KRT 81; KRT81; KRT81_HUMAN; KRTHB 1; KRTHB1; Metastatic lymph node 137 gene protein; MLN 137; MLN137; type II cuticular Hb1; Type II hair keratin Hb1; Type-II keratin Kb21;

抗原和靶标

免疫原:
Uniprot:

O43790(KRT86_HUMAN) >>Visit HPA database.

Q14533(KRT81_HUMAN) >>Visit HPA database.

基因/基因ID:
KRT86(3892) | KRT81(3887)
表达:
O43790 KRT86_HUMAN:

Synthesis begins slightly higher in the hair shaft than HB1 and HB3 and continues much farther up, ending in the keratogeneous zone.

Q14533 KRT81_HUMAN:

Abundantly expressed in the differentiating cortex of growing (anagen) hair. Expression is restricted to the keratinocytes of the hair cortex and is absent from inner root sheath and medulla. Expressed in malignant lymph node tissue in breast carcinoma tissue.

序列:
MTCGSYCGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEGVGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNSNVVVGTTNACAPSARVGVCGGSCKRC

MTCGSGFGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEILILQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEGIGAVNVCVSSSRGGVVCGDLCVSGSRPVTGSVCSAPCNGNVAVSTGLCAPCGQLNTTCGGGSCGVGSCGISSLGVGSCGSSCRKC

翻译修饰 - O43790/Q14533 作为底物

Site PTM Type Enzyme
S47 Phosphorylation
S49 Phosphorylation
K132 Ubiquitination
K193 Methylation
T203 Phosphorylation
K222 Methylation
Y243 Phosphorylation
Y282 Phosphorylation
Y297 Phosphorylation
K300 Ubiquitination
K305 Ubiquitination
T307 Phosphorylation
T314 Phosphorylation
T318 Phosphorylation
K319 Ubiquitination
K340 Ubiquitination
K345 Ubiquitination
K367 Ubiquitination
K377 Methylation
K377 Ubiquitination
K379 Ubiquitination
S395 Phosphorylation
S455 Phosphorylation
S460 Phosphorylation
T466 Phosphorylation
S482 Phosphorylation
Site PTM Type Enzyme
S47 Phosphorylation
S49 Phosphorylation
K132 Ubiquitination
T203 Phosphorylation
S252 Phosphorylation
S258 Phosphorylation
Y282 Phosphorylation
Y297 Phosphorylation
K300 Ubiquitination
K305 Ubiquitination
T307 Phosphorylation
T314 Phosphorylation
T318 Phosphorylation
K319 Ubiquitination
K340 Ubiquitination
K345 Ubiquitination
K367 Ubiquitination
K377 Ubiquitination
K379 Ubiquitination
S395 Phosphorylation

研究背景

组织特异性:

Synthesis begins slightly higher in the hair shaft than HB1 and HB3 and continues much farther up, ending in the keratogeneous zone.

亚基结构:

Heterotetramer of two type I and two type II keratins.

蛋白家族:

Belongs to the intermediate filament family.

组织特异性:

Abundantly expressed in the differentiating cortex of growing (anagen) hair. Expression is restricted to the keratinocytes of the hair cortex and is absent from inner root sheath and medulla. Expressed in malignant lymph node tissue in breast carcinoma tissue.

亚基结构:

Heterotetramer of two type I and two type II keratins.

蛋白家族:

Belongs to the intermediate filament family.

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