| 产品: | CSNK1G3 抗体 |
| 货号: | DF10135 |
| 描述: | Rabbit polyclonal antibody to CSNK1G3 |
| 应用: | WB IHC |
| 反应: | Human, Mouse, Rat |
| 预测: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Xenopus |
| 分子量: | 51 kDa; 51kD(Calculated). |
| 蛋白号: | Q9Y6M4 |
| RRID: | AB_2840715 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF10135, RRID:AB_2840715.
展开/折叠
casein kinase 1 gamma 3; casein kinase I gamma 3; Casein kinase I isoform gamma 3; Casein kinase I isoform gamma-3; CKI-gamma 3; Csnk1g3; CSNK1G3L; KC1G3_HUMAN;
抗原和靶标
- Q9Y6M4 KC1G3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MENKKKDKDKSDDRMARPSGRSGHNTRGTGSSSSGVLMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSGDGIPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGNKTQQVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRKGYMFDYEYDWIGKQLPTPVGAVQQDPALSSNREAHQHRDKMQQSKNQSADHRAAWDSQQANPHHLRAHLAADRHGGSVQVVSSTNGELNTDDPTAGRSNAPITAPTEVEVMDETKCCCFFKRRKRKTIQRHK
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q9Y6M4 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| M1 | Acetylation | Uniprot | |
| S11 | Phosphorylation | Uniprot | |
| T29 | Phosphorylation | Uniprot | |
| S31 | Phosphorylation | Uniprot | |
| S32 | Phosphorylation | Uniprot | |
| S34 | Phosphorylation | Uniprot | |
| K48 | Ubiquitination | Uniprot | |
| K61 | Ubiquitination | Uniprot | |
| Y64 | Phosphorylation | Uniprot | |
| T65 | Phosphorylation | Uniprot | |
| Y68 | Phosphorylation | Uniprot | |
| Y87 | Phosphorylation | Uniprot | |
| Y90 | Phosphorylation | Uniprot | |
| K91 | Methylation | Uniprot | |
| Y160 | Phosphorylation | Uniprot | |
| K164 | Ubiquitination | Uniprot | |
| K176 | Ubiquitination | Uniprot | |
| Y192 | Phosphorylation | Uniprot | |
| K253 | Ubiquitination | Uniprot | |
| T256 | Phosphorylation | Uniprot | |
| K263 | Ubiquitination | Uniprot | |
| K306 | Ubiquitination | Uniprot | |
| S344 | Phosphorylation | Uniprot | |
| S345 | Phosphorylation | Uniprot | |
| S392 | Phosphorylation | Uniprot | |
| S397 | Phosphorylation | Uniprot | |
| S398 | Phosphorylation | Uniprot | |
| S413 | Phosphorylation | Uniprot | |
| T421 | Phosphorylation | Uniprot | |
| K430 | Ubiquitination | Uniprot | |
| K436 | Ubiquitination | Uniprot |
研究背景
Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Regulates fast synaptic transmission mediated by glutamate (By similarity).
Autophosphorylated.
Cytoplasm.
Monomer.
Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.
研究领域
· Environmental Information Processing > Signal transduction > Hedgehog signaling pathway. (View pathway)
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