产品: CD1B 抗体
货号: DF10150
描述: Rabbit polyclonal antibody to CD1B
应用: WB
反应: Human, Rat
预测: Dog
分子量: 37 kDa; 37kD(Calculated).
蛋白号: P29016
RRID: AB_2840729

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   规格 价格 库存
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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产品描述

来源:
Rabbit
应用:
WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Rat
预测:
Dog(88%)
克隆:
Polyclonal
特异性:
CD1B Antibody detects endogenous levels of total CD1B.
RRID:
AB_2840729
引用格式: Affinity Biosciences Cat# DF10150, RRID:AB_2840729.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

A1 domain; CD1; CD1A; CD1b; CD1b antigen; CD1B antigen b polypeptide; CD1b molecule; CD1B_HUMAN; Cortical thymocyte antigen CD1A; Cortical thymocyte antigen CD1B; Differentiation antigen CD1 alpha 3; hTa1 thymocyte antigen; Ly38; Ly38; T cell surface glycoprotein CD1a; MGC125990; MGC125991; R1; T-cell surface glycoprotein CD1b; T6/Leu6; Thymocite antigen CD1B;

抗原和靶标

免疫原:
Uniprot:
基因/基因ID:
表达:
P29016 CD1B_HUMAN:

Expressed on cortical thymocytes, on certain T-cell leukemias, and in various other tissues.

序列:
MLLLPFQLLAVLFPGGNSEHAFQGPTSFHVIQTSSFTNSTWAQTQGSGWLDDLQIHGWDSDSGTAIFLKPWSKGNFSDKEVAELEEIFRVYIFGFAREVQDFAGDFQMKYPFEIQGIAGCELHSGGAIVSFLRGALGGLDFLSVKNASCVPSPEGGSRAQKFCALIIQYQGIMETVRILLYETCPRYLLGVLNAGKADLQRQVKPEAWLSSGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQQGTQLGDILPNANWTWYLRATLDVADGEAAGLSCRVKHSSLEGQDIILYWRNPTSIGSIVLAIIVPSLLLLLCLALWYMRRRSYQNIP

种属预测

种属预测:

score>80的预测可信度较高,可尝试用于WB检测。*预测模型主要基于免疫原序列比对,结果仅作参考,不作为质保凭据。

Species
Results
Score
Dog
88
Pig
0
Horse
0
Bovine
0
Sheep
0
Xenopus
0
Zebrafish
0
Chicken
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - P29016 作为底物

Site PTM Type Enzyme
N38 N-Glycosylation
N75 N-Glycosylation
Y110 Phosphorylation
K145 Ubiquitination
K196 Ubiquitination
K204 Ubiquitination

研究背景

功能:

Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells.

细胞定位:

Cell membrane>Single-pass type I membrane protein. Endosome membrane>Single-pass type I membrane protein. Lysosome membrane>Single-pass type I membrane protein.
Note: Subject to intracellular trafficking between the cell membrane, endosomes and lysosomes.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Expressed on cortical thymocytes, on certain T-cell leukemias, and in various other tissues.

亚基结构:

Heterodimer with B2M (beta-2-microglobulin). Interacts with saposin C.

研究领域

· Cellular Processes > Cellular community - eukaryotes > Tight junction.   (View pathway)

· Organismal Systems > Immune system > Hematopoietic cell lineage.   (View pathway)

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