| 产品: | MOBL3 抗体 |
| 货号: | AF0726 |
| 描述: | Rabbit polyclonal antibody to MOBL3 |
| 应用: | WB |
| 反应: | Human, Mouse, Rat |
| 预测: | Zebrafish, Chicken, Xenopus |
| 分子量: | 26kDa; 26kD(Calculated). |
| 蛋白号: | Q9Y3A3 |
| RRID: | AB_2834354 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# AF0726, RRID:AB_2834354.
展开/折叠
2C4D; CGI 95; class II mMOB1; MGC12264; MOB family member 4, phocein; MOB like protein phocein; MOB1; mob1 homolog 3; MOB1, Mps One Binder kinase activator like 3; Mob3; MOB4; MOBKL3; MOBL3_HUMAN; mps one binder kinase activator like 3; Mps one binder kinase activator-like 3; Phocein Mob like protein; PHOCN; PREI3; Preimplantation protein 3; RCJMB04_1o21;
抗原和靶标
- Q9Y3A3 PHOCN_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MVMAEGTAVLRRNRPGTKAQDFYNWPDESFDEMDSTLAVQQYIQQNIRADCSNIDKILEPPEGQDEGVWKYEHLRQFCLELNGLAVKLQSECHPDTCTQMTATEQWIFLCAAHKTPKECPAIDYTRHTLDGAACLLNSNKYFPSRVSIKESSVAKLGSVCRRIYRIFSHAYFHHRQIFDEYENETFLCHRFTKFVMKYNLMSKDNLIVPILEEEVQNSVSGESEA
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q9Y3A3 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| C134 | S-Nitrosylation | Uniprot | |
| K140 | Acetylation | Uniprot | |
| K140 | Ubiquitination | Uniprot | |
| Y141 | Phosphorylation | Uniprot | |
| S147 | Phosphorylation | Uniprot | |
| K149 | Ubiquitination | Uniprot | |
| K155 | Acetylation | Uniprot | |
| T192 | Phosphorylation | Uniprot | |
| Y198 | Phosphorylation | Uniprot |
研究背景
May play a role in membrane trafficking, specifically in membrane budding reactions.
Phosphorylated on serine residues.
Cytoplasm>Perinuclear region. Membrane>Peripheral membrane protein. Golgi apparatus>Golgi stack membrane>Peripheral membrane protein.
Note: In a perinuclear punctate pattern. Associated with membranes and the Golgi stacks.
Binds STRN4 (By similarity). Interacts with DNM1 and EPS15 (By similarity). Interacts with nucleoside diphosphate kinase (By similarity). Binds STRN and STRN3. Part of a ternary complex containing MOB4/PHOCN, STRN and/or STRN3 and PPA2. Interacts with CTTNBP2 (By similarity). Interacts with CTTNBP2NL.
Belongs to the MOB1/phocein family.
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