产品: | GH1 抗体 |
货号: | DF10188 |
描述: | Rabbit polyclonal antibody to GH1 |
应用: | WB |
反应: | Human |
分子量: | 25 kDa; 25kD(Calculated). |
蛋白号: | P01241 |
RRID: | AB_2840767 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF10188, RRID:AB_2840767.
展开/折叠
gH; GH-N; GH1; GHB5; GHN; Growth hormone 1; Growth hormone; Growth hormone B5; Growth hormone, normal; Growth hormone, pituitary; HG1; hGH-N; IGHD1B; Pituitary growth hormone; RNGHGP; SOMA_HUMAN; Somatotropin;
抗原和靶标
- P01241 SOMA_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MATGSRTSLLLAFGLLCLPWLQEGSAFPTIPLSRLFDNAMLRAHRLHQLAFDTYQEFEEAYIPKEQKYSFLQNPQTSLCFSESIPTPSNREETQQKSNLELLRISLLLIQSWLEPVQFLRSVFANSLVYGASDSNVYDLLKDLEEGIQTLMGRLEDGSPRTGQIFKQTYSKFDTNSHNDDALLKNYGLLYCFRKDMDKVETFLRIVQCRSVEGSCGF
翻译修饰 - P01241 作为底物
Site | PTM Type | Enzyme | Source |
---|---|---|---|
Y68 | Phosphorylation | Uniprot | |
S77 | Phosphorylation | Uniprot | |
T93 | Phosphorylation | Uniprot | |
S97 | Phosphorylation | Uniprot | |
S132 | Phosphorylation | Uniprot | |
S176 | Phosphorylation | Uniprot |
研究背景
Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.
Secreted.
Monomer, dimer, trimer, tetramer and pentamer, disulfide-linked or non-covalently associated, in homopolymeric and heteropolymeric combinations. Can also form a complex either with GHBP or with the alpha2-macroglobulin complex.
Belongs to the somatotropin/prolactin family.
研究领域
· Environmental Information Processing > Signaling molecules and interaction > Cytokine-cytokine receptor interaction. (View pathway)
· Environmental Information Processing > Signaling molecules and interaction > Neuroactive ligand-receptor interaction.
· Environmental Information Processing > Signal transduction > PI3K-Akt signaling pathway. (View pathway)
· Environmental Information Processing > Signal transduction > Jak-STAT signaling pathway. (View pathway)
限制条款
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