| 产品: | TNFRSF17 抗体 |
| 货号: | DF10193 |
| 描述: | Rabbit polyclonal antibody to TNFRSF17 |
| 应用: | WB IF/ICC |
| 反应: | Human, Rat |
| 预测: | Horse, Dog |
| 分子量: | 20 kDa; 20kD(Calculated). |
| 蛋白号: | Q02223 |
| RRID: | AB_2840772 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF10193, RRID:AB_2840772.
展开/折叠
B cell maturation antigen; B cell maturation factor; B cell maturation protein; B-cell maturation protein; BCM; BCMA; CD269; CD269 antigen; TNFRSF17; TNR17_HUMAN; Tumor necrosis factor receptor superfamily member 17;
抗原和靶标
- Q02223 TNR17_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MLQMAGQCSQNEYFDSLLHACIPCQLRCSSNTPPLTCQRYCNASVTNSVKGTNAILWTCLGLSLIISLAVFVLMFLLRKINSEPLKDEFKNTGSGLLGMANIDLEKSRTGDEIILPRGLEYTVEECTCEDCIKSKPKVDSDHCFPLPAMEEGATILVTTKTNDYCKSLPAALSATEIEKSISAR
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q02223 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K86 | Acetylation | Uniprot | |
| K86 | Ubiquitination | Uniprot | |
| K106 | Acetylation | Uniprot | |
| K106 | Ubiquitination | Uniprot | |
| Y121 | Phosphorylation | Uniprot | |
| K133 | Ubiquitination | Uniprot | |
| K135 | Ubiquitination | Uniprot | |
| K137 | Ubiquitination | Uniprot | |
| K160 | Ubiquitination | Uniprot | |
| K166 | Ubiquitination | Uniprot | |
| S173 | Phosphorylation | Uniprot | |
| K179 | Ubiquitination | Uniprot |
研究背景
Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK.
Cell membrane>Single-pass type III membrane protein. Endomembrane system>Single-pass type III membrane protein.
Note: Perinuclear Golgi-like structures.
Expressed in mature B-cells, but not in T-cells or monocytes.
Associates with TRAF1, TRAF2, TRAF3, TRAF5 and TRAF6.
研究领域
· Environmental Information Processing > Signaling molecules and interaction > Cytokine-cytokine receptor interaction. (View pathway)
· Organismal Systems > Immune system > Intestinal immune network for IgA production. (View pathway)
限制条款
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