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| 产品: | CCR10 抗体 |
| 货号: | DF10204 |
| 描述: | Rabbit polyclonal antibody to CCR10 |
| 应用: | WB IHC |
| 反应: | Human, Mouse, Rat |
| 预测: | Rabbit |
| 分子量: | 38 kDa; 38kD(Calculated). |
| 蛋白号: | P46092 |
| RRID: | AB_2840783 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF10204, RRID:AB_2840783.
展开/折叠
C C chemokine receptor type 10; C-C chemokine receptor type 10; C-C CKR-10; CC chemokine receptor 10; CC CKR 10; CC-CKR-10; CCR-10; CCR10; CCR10_HUMAN; Chemokine (C C motif) receptor 10; G protein coupled receptor 2; G-protein coupled receptor 2; GPR2;
抗原和靶标
Expressed at high levels in adult testis, small intestine, fetal lung, fetal kidney. Weaker expression was observed in many other adult tissues including spleen, thymus, lymph node, Peyer patches, colon, heart, ovary, peripheral blood lymphocytes, thyroid and spinal cord. Also expressed by melanocytes, dermal fibroblasts, dermal microvascular endothelial cells. Also detected in T-cells and in skin-derived Langerhans cells.
- P46092 CCR10_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGTEATEQVSWGHYSGDEEDAYSAEPLPELCYKADVQAFSRAFQPSVSLTVAALGLAGNGLVLATHLAARRAARSPTSAHLLQLALADLLLALTLPFAAAGALQGWSLGSATCRTISGLYSASFHAGFLFLACISADRYVAIARALPAGPRPSTPGRAHLVSVIVWLLSLLLALPALLFSQDGQREGQRRCRLIFPEGLTQTVKGASAVAQVALGFALPLGVMVACYALLGRTLLAARGPERRRALRVVVALVAAFVVLQLPYSLALLLDTADLLAARERSCPASKRKDVALLVTSGLALARCGLNPVLYAFLGLRFRQDLRRLLRGGSCPSGPQPRRGCPRRPRLSSCSAPTETHSLSWDN
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P46092 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K286 | Acetylation | Uniprot | |
| T295 | Phosphorylation | Uniprot | |
| S296 | Phosphorylation | Uniprot | |
| S329 | Phosphorylation | Uniprot |
研究背景
Receptor for chemokines SCYA27 and SCYA28. Subsequently transduces a signal by increasing the intracellular calcium ions level and stimulates chemotaxis in a pre-B cell line.
Cell membrane>Multi-pass membrane protein.
Expressed at high levels in adult testis, small intestine, fetal lung, fetal kidney. Weaker expression was observed in many other adult tissues including spleen, thymus, lymph node, Peyer patches, colon, heart, ovary, peripheral blood lymphocytes, thyroid and spinal cord. Also expressed by melanocytes, dermal fibroblasts, dermal microvascular endothelial cells. Also detected in T-cells and in skin-derived Langerhans cells.
Belongs to the G-protein coupled receptor 1 family.
研究领域
· Environmental Information Processing > Signaling molecules and interaction > Cytokine-cytokine receptor interaction. (View pathway)
· Organismal Systems > Immune system > Chemokine signaling pathway. (View pathway)
· Organismal Systems > Immune system > Intestinal immune network for IgA production. (View pathway)
文献引用
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