产品: | TAS2R38 抗体 |
货号: | DF10267 |
描述: | Rabbit polyclonal antibody to TAS2R38 |
应用: | WB IHC |
反应: | Human, Mouse, Rat |
预测: | Pig, Sheep |
分子量: | 38 kDa; 38kD(Calculated). |
蛋白号: | P59533 |
RRID: | AB_2840845 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF10267, RRID:AB_2840845.
展开/折叠
PTC; PTC bitter taste receptor; T2R38; T2R38_HUMAN; T2R61; TAS2R38; Taste receptor type 2 member 38; Taste receptor type 2 member 61; taste receptor, type 2, member 38;
抗原和靶标
Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells. Expressed in testis (PubMed:16720576).
- P59533 T2R38_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MLTLTRIRTVSYEVRSTFLFISVLEFAVGFLTNAFVFLVNFWDVVKRQALSNSDCVLLCLSISRLFLHGLLFLSAIQLTHFQKLSEPLNHSYQAIIMLWMIANQANLWLAACLSLLYCSKLIRFSHTFLICLASWVSRKISQMLLGIILCSCICTVLCVWCFFSRPHFTVTTVLFMNNNTRLNWQIKDLNLFYSFLFCYLWSVPPFLLFLVSSGMLTVSLGRHMRTMKVYTRNSRDPSLEAHIKALKSLVSFFCFFVISSCAAFISVPLLILWRDKIGVMVCVGIMAACPSGHAAILISGNAKLRRAVMTILLWAQSSLKVRADHKADSRTLC
种属预测
score>80的预测可信度较高,可尝试用于WB检测。*预测模型主要基于免疫原序列比对,结果仅作参考,不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P59533 作为底物
Site | PTM Type | Enzyme | Source |
---|---|---|---|
T5 | Phosphorylation | Uniprot | |
S291 | Phosphorylation | Uniprot |
研究背景
Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity).
Membrane>Multi-pass membrane protein.
Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells. Expressed in testis.
Belongs to the G-protein coupled receptor T2R family.
研究领域
· Organismal Systems > Sensory system > Taste transduction.
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