产品: CCR9 抗体
货号: DF2910
描述: Rabbit polyclonal antibody to CCR9
应用: WB IF/ICC
反应: Human, Mouse, Rat
预测: Pig, Horse, Sheep, Rabbit, Dog
分子量: 45kDa; 42kD(Calculated).
蛋白号: P51686
RRID: AB_2840899

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   规格 价格 库存
 50ul RMB¥ 1250 现货
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 200ul RMB¥ 3000 现货

货期: 当天发货

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产品描述

来源:
Rabbit
应用:
WB 1:1000-3000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse,Rat
预测:
Pig(100%), Horse(100%), Sheep(100%), Rabbit(100%), Dog(92%)
克隆:
Polyclonal
特异性:
CCR9 Antibody detects endogenous levels of total CCR9.
RRID:
AB_2840899
引用格式: Affinity Biosciences Cat# DF2910, RRID:AB_2840899.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

C C chemokine receptor D6; C C chemokine receptor type 9; C C CKR 9; CC Chemokine receptor CCR10; CC CKR 9; CCBP2; CCCKR9; CCR 9; CCR9; CDw199; CDw199 antigen; Chemokine (C C motif) receptor 9; Chemokine (C C motif) receptor 9, isoform CRA_a; Chemokine (C-C motif) receptor 9 isoform A; Chemokine (C-C motif) receptor 9 isoform B; Chemokine C C motif receptor 9; Chemokine C C receptor 10; Chemokine CC Motif Receptor 9; Chemokine receptor CCR 9; Chemokine receptor CCR9; Chemokine-binding protein D6; Cmkbr10; CMKBR9; G protein coupled receptor 28; GPR 28; GPR 9 6; GPR28; GPR96; OTTHUMP00000164653; OTTHUMP00000164654;

抗原和靶标

免疫原:
Uniprot:
基因/基因ID:
表达:
P51686 CCR9_HUMAN:

Highly expressed in the thymus and low in lymph nodes and spleen.

序列:
MTPTDFTSPIPNMADDYGSESTSSMEDYVNFNFTDFYCEKNNVRQFASHFLPPLYWLVFIVGALGNSLVILVYWYCTRVKTMTDMFLLNLAIADLLFLVTLPFWAIAAADQWKFQTFMCKVVNSMYKMNFYSCVLLIMCISVDRYIAIAQAMRAHTWREKRLLYSKMVCFTIWVLAAALCIPEILYSQIKEESGIAICTMVYPSDESTKLKSAVLTLKVILGFFLPFVVMACCYTIIIHTLIQAKKSSKHKALKVTITVLTVFVLSQFPYNCILLVQTIDAYAMFISNCAVSTNIDICFQVTQTIAFFHSCLNPVLYVFVGERFRRDLVKTLKNLGCISQAQWVSFTRREGSLKLSSMLLETTSGALSL

种属预测

种属预测:

score>80的预测可信度较高,可尝试用于WB检测。*预测模型主要基于免疫原序列比对,结果仅作参考,不作为质保凭据。

Species
Results
Score
Pig
100
Horse
100
Sheep
100
Rabbit
100
Dog
92
Bovine
0
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - P51686 作为底物

Site PTM Type Enzyme
T81 Phosphorylation
T83 Phosphorylation
Y145 Phosphorylation
S368 Phosphorylation

研究背景

功能:

Receptor for chemokine SCYA25/TECK. Subsequently transduces a signal by increasing the intracellular calcium ions level.

(Microbial infection) Alternative coreceptor with CD4 for HIV-1 infection.

细胞定位:

Cell membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Highly expressed in the thymus and low in lymph nodes and spleen.

蛋白家族:

Belongs to the G-protein coupled receptor 1 family.

研究领域

· Environmental Information Processing > Signaling molecules and interaction > Cytokine-cytokine receptor interaction.   (View pathway)

· Organismal Systems > Immune system > Chemokine signaling pathway.   (View pathway)

· Organismal Systems > Immune system > Intestinal immune network for IgA production.   (View pathway)

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