| 产品: | KLF11 抗体 |
| 货号: | DF3014 |
| 描述: | Rabbit polyclonal antibody to KLF11 |
| 应用: | WB IF/ICC |
| 反应: | Human, Mouse |
| 预测: | Dog |
| 分子量: | 55 KD; 55kD(Calculated). |
| 蛋白号: | O14901 |
| RRID: | AB_2840993 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF3014, RRID:AB_2840993.
展开/折叠
9830142A17; D12Ertd427e; FKLF; FKLF1; Klf11; KLF11_HUMAN; Krueppel like factor 11; Krueppel-like factor 11; Krueppel-like transcription factor 1; MODY7; Tcfcp2l2; TGFB Early Growth Response 2; TGFB-inducible early growth response protein 2; TGFB-inducible early growth response protein 2b; TGFB-inducible early growth response protein 3; TIEG 2; TIEG-2; TIEG-3; Tieg2b; Transforming Growth Factor Beta Inducible Early Growth Response 2; Transforming growth factor-beta-inducible early growth response protein 2; Transforming growth factor-beta-inducible early growth response protein 3;
抗原和靶标
- O14901 KLF11_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MHTPDFAGPDDARAVDIMDICESILERKRHDSERSTCSILEQTDMEAVEALVCMSSWGQRSQKGDLLRIRPLTPVSDSGDVTTTVHMDAATPELPKDFHSLSTLCITPPQSPDLVEPSTRTPVSPQVTDSKACTATDVLQSSAVVARALSGGAERGLLGLEPVPSSPCRAKGTSVIRHTGESPAACFPTIQTPDCRLSDSREGEEQLLGHFETLQDTHLTDSLLSTNLVSCQPCLHKSGGLLLTDKGQQAGWPGAVQTCSPKNYENDLPRKTTPLISVSVPAPPVLCQMIPVTGQSSMLPAFLKPPPQLSVGTVRPILAQAAPAPQPVFVGPAVPQGAVMLVLPQGALPPPAPCAANVMAAGNTKLLPLAPAPVFITSSQNCVPQVDFSRRRNYVCSFPGCRKTYFKSSHLKAHLRTHTGEKPFNCSWDGCDKKFARSDELSRHRRTHTGEKKFVCPVCDRRFMRSDHLTKHARRHMTTKKIPGWQAEVGKLNRIASAESPGSPLVSMPASA
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - O14901 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T73 | Phosphorylation | Uniprot | |
| T82 | Phosphorylation | Uniprot | |
| T83 | Phosphorylation | Uniprot | |
| T107 | Phosphorylation | Uniprot | |
| S111 | Phosphorylation | Uniprot | |
| S124 | Phosphorylation | Uniprot | |
| S150 | Phosphorylation | Uniprot | |
| S166 | Phosphorylation | Uniprot | |
| K403 | Ubiquitination | Uniprot | |
| K412 | Sumoylation | Uniprot | |
| K412 | Ubiquitination | Uniprot | |
| T417 | Phosphorylation | Uniprot | |
| T419 | Phosphorylation | Uniprot | |
| T447 | Phosphorylation | Uniprot | |
| T449 | Phosphorylation | Uniprot | |
| K471 | Ubiquitination | Uniprot |
研究背景
Transcription factor. Activates the epsilon- and gamma-globin gene promoters and, to a much lower degree, the beta-globin gene and represses promoters containing SP1-like binding inhibiting cell growth. Represses transcription of SMAD7 which enhances TGF-beta signaling (By similarity). Induces apoptosis (By similarity).
Nucleus.
Ubiquitous. Higher expression in erythroid cells.
Interacts with SIN3A.
Belongs to the Sp1 C2H2-type zinc-finger protein family.
限制条款
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