ADFP Antibody - #DF7603

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产品: ADFP 抗体
货号: DF7603
描述: Rabbit polyclonal antibody to ADFP
应用: WB
反应: Human, Mouse, Rat
预测: Pig, Bovine, Horse, Rabbit, Dog
分子量: 48 kDa; 48kD(Calculated).
蛋白号: Q99541
RRID: AB_2841094

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 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

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产品描述

来源:
Rabbit
应用:
WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse,Rat
预测:
Pig(100%), Bovine(100%), Horse(83%), Rabbit(92%), Dog(100%)
克隆:
Polyclonal
特异性:
ADFP Antibody detects endogenous levels of total ADFP.
RRID:
AB_2841094
引用格式: Affinity Biosciences Cat# DF7603, RRID:AB_2841094.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

ADFP; Adipophilin; Adipose differentiation related protein; Adipose differentiation-related protein; ADRP; MGC10598; Perilipin-2; PLIN2; PLIN2_HUMAN;

抗原和靶标

免疫原:
Uniprot:

Q99541(PLIN2_HUMAN) >>Visit HPA database.

基因/基因ID:
PLIN2(123)
表达:
Q99541 PLIN2_HUMAN:

Milk lipid globules.

序列:
MASVAVDPQPSVVTRVVNLPLVSSTYDLMSSAYLSTKDQYPYLKSVCEMAENGVKTITSVAMTSALPIIQKLEPQIAVANTYACKGLDRIEERLPILNQPSTQIVANAKGAVTGAKDAVTTTVTGAKDSVASTITGVMDKTKGAVTGSVEKTKSVVSGSINTVLGSRMMQLVSSGVENALTKSELLVEQYLPLTEEELEKEAKKVEGFDLVQKPSYYVRLGSLSTKLHSRAYQQALSRVKEAKQKSQQTISQLHSTVHLIEFARKNVYSANQKIQDAQDKLYLSWVEWKRSIGYDDTDESHCAEHIESRTLAIARNLTQQLQTTCHTLLSNIQGVPQNIQDQAKHMGVMAGDIYSVFRNAASFKEVSDSLLTSSKGQLQKMKESLDDVMDYLVNNTPLNWLVGPFYPQLTESQNAQDQGAEMDKSSQETQRSEHKTH

种属预测

种属预测:

score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。

Species
Results
Score
Pig
100
Bovine
100
Dog
100
Rabbit
92
Horse
83
Sheep
0
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - Q99541 作为底物

Site PTM Type Enzyme
A2 Acetylation
K116 Ubiquitination
K140 Ubiquitination
S148 Phosphorylation
K153 Ubiquitination
S215 Phosphorylation
Y216 Phosphorylation
Y217 Phosphorylation
S222 Phosphorylation
S224 Phosphorylation
S237 Phosphorylation
S255 Phosphorylation
K273 Ubiquitination
S291 Phosphorylation
S362 Phosphorylation
K375 Ubiquitination

研究背景

功能:

May be involved in development and maintenance of adipose tissue.

翻译修饰:

Acylated; primarily with C14, C16 and C18 fatty acids.

细胞定位:

Membrane>Peripheral membrane protein. Lipid droplet.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Milk lipid globules.

蛋白家族:

Belongs to the perilipin family.

研究领域

· Organismal Systems > Endocrine system > PPAR signaling pathway.

文献引用

1). Preventive Effects of Ilex Cornuta Aqueous Extract on High-Fat Diet-Induced Fatty Liver of Mice. Evidence-Based Complementary and Alternative Medicine (PubMed: 35432557)

Application: WB    Species: Mouse    Sample: liver

Figure 6 Effects of ICAE on the protein expression of PPARγ and ADRP in the liver of HFD-induced mice. The protein levels of PPARγ (a) and ADRP (b) were detected by immunoblot. Images were representative of three independent experiments, and average protein levels were quantified as ratios to β-actin, n = 5–6. ∗P < 0.05, ∗∗P < 0.01vs control; #P < 0.05, ####P < 0.0001vs. HFD group.

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