| 产品: | RHOQ 抗体 |
| 货号: | DF7643 |
| 描述: | Rabbit polyclonal antibody to RHOQ |
| 应用: | WB IHC |
| 反应: | Human, Mouse, Rat |
| 预测: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken |
| 分子量: | 25 kDa; 23kD(Calculated). |
| 蛋白号: | P17081 |
| RRID: | AB_2841123 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF7643, RRID:AB_2841123.
展开/折叠
ARHQ; Ras homolog gene family member Q; RAS like family 7 member A; Ras like protein family member 7A; Ras like protein TC10; Ras related GTP binding protein TC10; Ras-like protein family member 7A; Ras-like protein TC10; RASL7A; Rho related GTP binding protein RhoQ; Rho-related GTP-binding protein RhoQ; Rhoq; RHOQ_HUMAN; TC10A;
抗原和靶标
- P17081 RHOQ_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAHGPGALMLKCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAVSVTVGGKQYLLGLYDTAGQEDYDRLRPLSYPMTDVFLICFSVVNPASFQNVKEEWVPELKEYAPNVPFLLIGTQIDLRDDPKTLARLNDMKEKPICVEQGQKLAKEIGACCYVECSALTQKGLKTVFDEAIIAILTPKKHTVKKRIGSRCINCCLIT
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P17081 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y70 | Phosphorylation | Uniprot | |
| K169 | Ubiquitination | Uniprot | |
| K172 | Ubiquitination | Uniprot | |
| T173 | Phosphorylation | Uniprot | |
| T189 | Phosphorylation | Uniprot |
研究背景
Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. May play a role in CFTR trafficking to the plasma membrane. Causes the formation of thin, actin-rich surface projections called filopodia.
May be post-translationally modified by both palmitoylation and polyisoprenylation.
Cytoplasm. Cell membrane>Lipid-anchor.
Interacts with CDC42EP4 in a GTP-dependent manner. Interacts with ARHGAP33/TCGAP (By similarity). Interacts with CDC42EP1, CDC42EP2, CDC42EP3, PARD6A, PARD6G (and probably PARD6B) in a GTP-dependent manner. Part of a quaternary complex containing PARD3, some PARD6 protein (PARD6A, PARD6B or PARD6G) and some atypical PKC protein (PRKCI or PRKCZ). Interacts with EXO70 in a GTP-dependent manner. Interacts with GOPC.
Belongs to the small GTPase superfamily. Rho family.
研究领域
· Organismal Systems > Endocrine system > Insulin signaling pathway. (View pathway)
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