| 产品: | GPRIN1 抗体 |
| 货号: | AF0664 |
| 描述: | Rabbit polyclonal antibody to GPRIN1 |
| 应用: | WB IF/ICC |
| 反应: | Human |
| 预测: | Bovine, Horse, Sheep, Dog |
| 分子量: | 102kDa; 102kD(Calculated). |
| 蛋白号: | Q7Z2K8 |
| RRID: | AB_2834395 |
产品描述
来源:
Rabbit
应用:
WB 1:500-1:2000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
反应:
Human
预测:
Bovine(100%), Horse(82%), Sheep(100%), Dog(91%)
克隆:
Polyclonal
特异性:
GPRIN1 Antibody detects endogenous levels of total GPRIN1.
RRID:
AB_2834395
引用格式: Affinity Biosciences Cat# AF0664, RRID:AB_2834395.
引用格式: Affinity Biosciences Cat# AF0664, RRID:AB_2834395.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:
展开/折叠
G protein regulated inducer of neurite outgrowth 1; G protein-regulated inducer of neurite outgrowth 1; GPRIN1; GRIN1; GRIN1_HUMAN; KIAA1893; Z16;
抗原和靶标
免疫原:
Uniprot:
基因/基因ID:
表达:
Q7Z2K8 GRIN1_HUMAN:
Widely expressed in the central nervous system, with highest levels in spinal cord.
描述:
GRIN1 May be involved in neurite outgrowth. Interacts with activated forms of GNAI1, GNAO1 and GNAZ. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
序列:
- Q7Z2K8 GRIN1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MDTAEDPAWLQLLQKDSSPPGPRPTAFFCPQDGSLGAGSSAMRDYCPSQQKASPAPPRHTPDQSPGMESRHRSPSGAGEGASCSDGPRGSLACPSPTCFSPQESPSKETLEAHGASISGTPEATTSGKPEPVSSVKTEPKSSDDRNPMFLEKMDFKSSKQADSTSIGKEDPGSSRKADPMFTGKAEPEILGKGDPVAPGRMDPMTVRKEDLGSLGKVDPLCSSKTYTVSPRKEDPGSLRKVDPVSSDKVDPVFPRKEEPRYSGKEHPVSSEKVAPTSAEKVDLVLSGKRDPGPSGKADPMPLESMDSASTGKTEPGLLGKLIPGSSGKNGPVSSGTGAPGSLGRLDPTCLGMADPASVGNVETVPATKEDSRFLGKMDPASSGEGRPVSGHTDTTASAKTDLTSLKNVDPMSSGKVDPVSLGKMDPMCSGKPELLSPGQAERVSVGKAGTVSPGKEDPVSSRREDPISAGSRKTSSEKVNPESSGKTNPVSSGPGDPRSLGTAGPPSAVKAEPATGGKGDPLSSEKAGLVASGKAAPTASGKAEPLAVGKEDPVSKGKADAGPSGQGDSVSIGKVVSTPGKTVPVPSGKVDPVSLGKAEAIPEGKVGSLPLEKGSPVTTTKADPRASGKAQPQSGGKAETKLPGQEGAAAPGEAGAVCLKKETPQASEKVDPGSCRKAEPLASGKGEPVSLGKADSAPSRKTESPSLGKVVPLSLEKTKPSSSSRQLDRKALGSARSPEGARGSEGRVEPKAEPVSSTEASSLGQKDLEAAGAERSPCPEAAAPPPGPRTRDNFTKAPSWEASAPPPPREDAGTQAGAQACVSVAVSPMSPQDGAGGSAFSFQAAPRAPSPPSRRDAGLQVSLGAAETRSVATGPMTPQAAAPPAFPEVRVRPGSALAAAVAPPEPAEPVRDVSWDEKGMTWEVYGAAMEVEVLGMAIQKHLERQIEEHGRQGAPAPPPAARAGPGRSGSVRTAPPDGAAKRPPGLFRALLQSVRRPRCCSRAGPTAE
种属预测
种属预测:
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
Species
Results
Score
Bovine
100
Sheep
100
Dog
91
Horse
82
Pig
73
Chicken
71
Xenopus
0
Zebrafish
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q7Z2K8 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T25 | Phosphorylation | Uniprot | |
| Y45 | Phosphorylation | Uniprot | |
| S53 | Phosphorylation | Uniprot | |
| T60 | Phosphorylation | Uniprot | |
| S64 | Phosphorylation | Uniprot | |
| S73 | Phosphorylation | Uniprot | |
| S75 | Phosphorylation | Uniprot | |
| S95 | Phosphorylation | Uniprot | |
| T97 | Phosphorylation | Uniprot | |
| S104 | Phosphorylation | Uniprot | |
| S116 | Phosphorylation | Uniprot | |
| T120 | Phosphorylation | Uniprot | |
| T182 | Phosphorylation | Uniprot | |
| T225 | Phosphorylation | Uniprot | |
| Y226 | Phosphorylation | Uniprot | |
| S229 | Phosphorylation | Uniprot | |
| S237 | Phosphorylation | Uniprot | |
| S286 | Phosphorylation | Uniprot | |
| T313 | Phosphorylation | Uniprot | |
| S334 | Phosphorylation | Uniprot | |
| T336 | Phosphorylation | Uniprot | |
| S341 | Phosphorylation | Uniprot | |
| S389 | Phosphorylation | Uniprot | |
| S436 | Phosphorylation | Uniprot | |
| S444 | Phosphorylation | Uniprot | |
| T450 | Phosphorylation | Uniprot | |
| S452 | Phosphorylation | Uniprot | |
| S476 | Phosphorylation | Uniprot | |
| S491 | Phosphorylation | Uniprot | |
| S507 | Phosphorylation | Uniprot | |
| T515 | Phosphorylation | Uniprot | |
| S540 | Phosphorylation | Uniprot | |
| S571 | Phosphorylation | Uniprot | |
| S577 | Phosphorylation | Uniprot | |
| S608 | Phosphorylation | Uniprot | |
| S615 | Phosphorylation | Uniprot | |
| T618 | Phosphorylation | Uniprot | |
| S634 | Phosphorylation | Uniprot | |
| S704 | Phosphorylation | Uniprot | |
| S706 | Phosphorylation | Uniprot | |
| S714 | Phosphorylation | Uniprot | |
| S734 | Phosphorylation | Uniprot | |
| S737 | Phosphorylation | Uniprot | |
| S744 | Phosphorylation | Uniprot | |
| S776 | Phosphorylation | Uniprot | |
| S799 | Phosphorylation | Uniprot | |
| S850 | Phosphorylation | Uniprot | |
| S853 | Phosphorylation | Uniprot | |
| S862 | Phosphorylation | Uniprot | |
| T873 | Phosphorylation | Uniprot | |
| T877 | Phosphorylation | Uniprot | |
| S895 | Phosphorylation | Uniprot | |
| S914 | Phosphorylation | Uniprot | |
| R962 | Methylation | Uniprot | |
| R967 | Methylation | Uniprot | |
| S968 | Phosphorylation | Uniprot | |
| S970 | Phosphorylation | Uniprot | |
| T973 | Phosphorylation | Uniprot | |
| S993 | Phosphorylation | Uniprot |
研究背景
功能:
May be involved in neurite outgrowth.
翻译修饰:
Palmitoylation on Cys-999 and/or Cys-1000 is required for membrane targeting.
细胞定位:
Cell membrane>Lipid-anchor. Cell projection>Growth cone.
Note: Highly enriched in growth cone.
组织特异性:
Widely expressed in the central nervous system, with highest levels in spinal cord.
亚基结构:
Interacts with activated forms of GNAI1, GNAO1 and GNAZ.
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