| 产品: | SPEE 抗体 |
| 货号: | DF7732 |
| 描述: | Rabbit polyclonal antibody to SPEE |
| 应用: | WB IHC |
| 反应: | Human, Mouse, Rat |
| 预测: | Pig, Zebrafish, Bovine, Horse, Sheep, Dog, Chicken, Xenopus |
| 分子量: | 33 kDa; 34kD(Calculated). |
| 蛋白号: | P19623 |
| RRID: | AB_2841200 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF7732, RRID:AB_2841200.
展开/折叠
OTTHUMP00000002170; PAPT; Putrescine aminopropyltransferase; SPDSY; SPEE_HUMAN; Spermidine synthase 1; Spermidine synthase; SPS1; Srm; SRML1;
抗原和靶标
- P19623 SPEE_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MEPGPDGPAASGPAAIREGWFRETCSLWPGQALSLQVEQLLHHRRSRYQDILVFRSKTYGNVLVLDGVIQCTERDEFSYQEMIANLPLCSHPNPRKVLIIGGGDGGVLREVVKHPSVESVVQCEIDEDVIQVSKKFLPGMAIGYSSSKLTLHVGDGFEFMKQNQDAFDVIITDSSDPMGPAESLFKESYYQLMKTALKEDGVLCCQGECQWLHLDLIKEMRQFCQSLFPVVAYAYCTIPTYPSGQIGFMLCSKNPSTNFQEPVQPLTQQQVAQMQLKYYNSDVHRAAFVLPEFARKALNDVS
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P19623 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| M1 | Acetylation | Uniprot | |
| R17 | Methylation | Uniprot | |
| R22 | Methylation | Uniprot | |
| Y48 | Phosphorylation | Uniprot | |
| C71 | S-Nitrosylation | Uniprot | |
| T72 | Phosphorylation | Uniprot | |
| K96 | Ubiquitination | Uniprot | |
| K113 | Ubiquitination | Uniprot | |
| S116 | Phosphorylation | Uniprot | |
| K134 | Ubiquitination | Uniprot | |
| K135 | Ubiquitination | Uniprot | |
| S147 | Phosphorylation | Uniprot | |
| K194 | Ubiquitination | Uniprot | |
| K198 | Ubiquitination | Uniprot | |
| K253 | Sumoylation | Uniprot | |
| K253 | Ubiquitination | Uniprot | |
| K277 | Sumoylation | Uniprot | |
| K277 | Ubiquitination | Uniprot | |
| K296 | Sumoylation | Uniprot | |
| K296 | Ubiquitination | Uniprot |
研究背景
Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM). Has a strong preference for putrescine as substrate, and has very low activity towards 1,3-diaminopropane. Has extremely low activity towards spermidine.
Homodimer or homotetramer.
Belongs to the spermidine/spermine synthase family.
研究领域
· Metabolism > Amino acid metabolism > Cysteine and methionine metabolism.
· Metabolism > Amino acid metabolism > Arginine and proline metabolism.
· Metabolism > Metabolism of other amino acids > beta-Alanine metabolism.
· Metabolism > Metabolism of other amino acids > Glutathione metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
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