GLP1R Antibody - #DF7750

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产品: GLP1R 抗体
货号: DF7750
描述: Rabbit polyclonal antibody to GLP1R
应用: WB
反应: Human, Rat
预测: Pig, Bovine, Horse, Sheep, Rabbit, Dog
分子量: 53 kDa;
蛋白号: p43220
RRID: AB_2841216

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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MS Report
HPLC Report
MSDS
说明书
COA
实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Rat
预测:
Pig(100%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(100%), Dog(100%)
克隆:
Polyclonal
特异性:
GLP1R Antibody detects endogenous levels of total GLP1R.
RRID:
AB_2841216
引用格式: Affinity Biosciences Cat# DF7750, RRID:AB_2841216.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

GLP 1 R; GLP 1 receptor; GLP 1R; GLP; GLP-1 receptor; GLP-1-R; GLP-1R; GLP1R; GLP1R_HUMAN; Glucagon like peptide 1 receptor; Glucagon-like peptide 1 receptor; MGC138331; OTTHUMP00000016340;

抗原和靶标

免疫原:
基因/基因ID:
GLP1R(2740)

种属预测

种属预测:

score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Rabbit
100
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

研究领域

· Environmental Information Processing > Signal transduction > cAMP signaling pathway.   (View pathway)

· Environmental Information Processing > Signaling molecules and interaction > Neuroactive ligand-receptor interaction.

· Organismal Systems > Endocrine system > Insulin secretion.   (View pathway)

文献引用

1). Geniposide ameliorates glucocorticoid-induced osteoblast apoptosis by activating autophagy. Biomedicine & Pharmacotherapy, 2022 (PubMed: 36271582) [IF=7.5]

Application: WB    Species: Rat    Sample: MC3T3-E1 cells

Fig. 8. GEN mediated autophagy by stimulating GLP-1R activity. The proteins expression of GLP-1R (A, B), PI3K (A, C), P-PI3K (A, D), AKT (A, E), P-AKT (A, F), mTOR (A, G), P-mTOR (A, H), P62 (A, I), LC3-II/I (A, J), Beclin-1 (A, K), and cleaved caspase3 (A, L) in DEX-treated MC3T3-E1 cells were determined by western blot. (M, N) The apoptosis was determined by a flow cytometer.
2). Effects of PPARD gene variants on the therapeutic responses to exenatide in chinese patients with type 2 diabetes mellitus. Frontiers in Endocrinology, 2022 (PubMed: 36051387) [IF=5.2]

Application: WB    Species: Human    Sample:

Figure 3 Effect of PPARδ agonists (GW501516) on the exenatide therapeutic efficacy by regulating the expression of GLP-1R. (A) Enzymatic methods were used to assay for glucose. (B) The mRNA level of GLP-1R was measured by RT-PCR. (C) The relative protein expression level of GLP-1R was measured by Western blot. Data are expressed as the mean ± SE, n = 3. * P < 0.05, ** P < 0.01 and *** P < 0.001 compared with IR. # P < 0.05, ## P < 0.01 and ### P < 0.001 compared with IR+Exendin-4.

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